Urinary Albumin Excretion
Conditions
Brief summary
PCO patients will be assessed clinically,urine & blood samples will be tested. Systolic & diastolic blood pressure, serum glucose & insulin levels, lipid profile, C-reactive protein, complete hormonal profile, and Urinary albumin excretion will be measured.
Detailed description
PCO patients with 2 of 3 criteria: oligo- or anovulation ; hyperandrogenism &polycystic ovaries. Exclusion criteria: pregnancy, diabetes, hypertension , adrenal & thyroid dysfunction. Blood samples after overnight fast (8hrs) at day 2 or 3 of menstrual cycle. Serum concentration of follicle stimulating hormone (FSH), luteinizing hormone (LH), prolactin, total testosterone & sex hormone binding globulin, serum 17-hydroxy (OH) progesterone & dehydroepiandrosterone sulfate will be measured. Oral glucose tolerance test & plasma insulin levels will be measured. Total cholesterol, triglycerides, high& low density lipoproteins. Urinary albumin will be measured& all the data will be analysed.
Interventions
None listed
Sponsors
Kasr El Aini Hospital
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
20 Years to 50 Years
Healthy volunteers
No
Inclusion criteria
* PCO patients
Exclusion criteria
* pregnancy * diabetes * hypertension * adrenal dysfunction * thyroid dysfunction
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of patients with hyperinsulinemia (uIU/ml) | 3 months |
| Number of patients with hyperlipidemia (mg/dl). | 3 months |
| Number of patients with albuminuria(ug/ml) | 3 months |
Contacts
Primary Contactsuzy abdelaziz, M.D.
Outcome results
None listed