Healthy
Conditions
Keywords
biobank, DNA, genetic, young adults, cohort study
Brief summary
The bio-Share project aims at collecting blood samples in students participating in the i-Share cohort (www.i-share.fr). Investigators aim at setting up a platform that will enable investigators in the future to study biological determinants of conditions that affect young adults and to test certain hypotheses on the pathophysiology and mechanisms underlying diseases occurring both at a young age and later in life (as early exposures may also impact late onset diseases)
Detailed description
The i-Share cohort was set up to study various important aspects of students' health and to better understand early mechanisms contributing to the occurrence of common diseases representing an important public health burden. The i-Share cohort is funded by an investment for the future grant from the French National Research Agency (ANR-10-COHO-05-01) with the aim to recruit 30000 students at the University of Bordeaux, and a few additional partner universities in France and abroad (www.i-share.fr). The bio-Share study is a biological repository embedded within the i-Share study, aiming at collecting blood samples (for genetic analyses as well as measurement of other biomarkers) from a subset of 2000 i-Share participants volunteering for this ancillary project. The goal is to set up a platform that will enable investigators in the future to study biological determinants of conditions that affect young adults and to test certain hypotheses on the pathophysiology and mechanisms underlying diseases occurring both at a young age and later in life (as early exposures may also impact late onset diseases). The biobank will comprise the following biological materials: plasma, serum, whole blood, red blood cells, DNA, RNA. Levels of fasting glucose and lipid levels (total cholesterol, HDL-cholesterol, LDL-cholesterol, triglycerides) will be returned to participants.
Interventions
None listed
Sponsors
National Research Agency, France
University Hospital, Bordeaux
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Be an i-Share participant in Bordeaux * Being aged 18 years or more * Being affiliated or beneficiary of a social security * Having filled out the first online i-Share questionnaire * Having signed a written informed consent
Exclusion criteria
* Pregnant or breastfeeding women, * Persons who cannot personally give their consent and adults under guardianship.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The acquisition date of blood samples | Day 1 |
| The number of the aliquots for each of the stored biological samples | Day 1 |
| The total volume of the aliquots for each of the stored biological samples | Day 1 |
Secondary
| Measure | Time frame |
|---|---|
| Low-density lipoprotein-cholesterol (fasting) | Day 1 |
| Glucose (fasting) | Day 1 |
| Triglycerides (fasting) | Day 1 |
| Total cholesterol (fasting) | Day 1 |
| High-density lipoprotein cholesterol (fasting) | Day 1 |
Countries
France
Outcome results
None listed