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The Physalis Child : Identification of Cognitive and Emotional Factors

Identification of Cognitive and Emotional Factors in Relation to Auditory Hallucinations in Non-psychotic Children

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02567500
Enrollment
40
Registered
2015-10-05
Start date
2015-07-07
Completion date
2017-07-07
Last updated
2018-07-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Auditory Hallucinations

Keywords

emotional, auditory hallucinations, non-psychotic children

Brief summary

The aim of this study is to show presence of cognitive and emotional factors on the beginning and persistence of auditory hallucinations in non-psychotic children. Investigators will describe a significant link between this factors and hallucinations in a sample of non-psychotic children. The results of this sample will be comparing to another group of children of the same age, sex and diagnosis, but without hallucination. Finally, investigators will control the persistence of hallucination on the first group after a six month period.

Detailed description

Background: Hallucinations are a common symptom in pediatric population without psychotic syndrome. Vulnerability, co morbidity and risk factor are already been described. Investigators will study the cognitive and emotional factors on the beginning and persistence of auditory hallucinations in non-psychotic children. The goal of the study is to find a social cognition our emotional impairment to explain auditory hallucinations without psychotic symptoms. Methods: Sample of out non-psychotic patients aged six to eighteen years old with auditory hallucinations were recruited with a self report scale created for this study. Mini International Neuropsychiatric Interview (MINI)-kids interview and psychosis section od Kiddie-SADS (Schedule for Affective Disorders and Schizophrenia for school age chidlren) were conducted to determine Diagnostic and Statistical Manual of Mental Disorders (DSM) IV diagnoses. All children patient were spend specifics social cognition (NeuroPsychologic assessment NEPSY II) and emotional (ifferential Emotions Scale (DES) IV, Beliefs About Voices Questionnaire Revised (BAVQ-R)) scales. Each child results will be compared to child result of the same age, sex and diagnosis but without hallucination that passed the same specifics scales. All of child will be control after a six month period to evaluate auditory hallucination persistence and diagnosis evolution. The total period of the study will be twelve month.

Interventions

BEHAVIORALPatients with auditory hallucination

Patients with auditory hallucination (20 for each arm): Evaluation at time 0 and 6 month after of: * The social cognitive marker (NEPSY II) : theory of mind and affect recognition * The emotional marker: * Differential emotion scale IV (DES IV): emotional individual stability * Revised Beliefs About Voices Questionnaire (BAVQ-R): a self report measure of patients' beliefs, emotional and behavior about auditory hallucination. * Evaluation of auditory hallucinations persistence with a self report scale using in recruiting criteria. * Evaluation of diagnosis with DSM-IV criteria: * MINI-Kids * Psychosis section of Kiddie-SADS

BEHAVIORALPatients without auditory hallucination

Patients without auditory hallucination (20 for each arm): Evaluation at time 0 and 6 month after of: * The social cognitive marker (NEPSY II) : theory of mind and affect recognition * The emotional marker: * Differential emotion scale IV (DES IV): emotional individual stability * Revised Beliefs About Voices Questionnaire (BAVQ-R): a self report measure of patients' beliefs, emotional and behavior about auditory hallucination. * Evaluation of auditory hallucinations persistence with a self report scale using in recruiting criteria. * Evaluation of diagnosis with DSM-IV criteria: * MINI-Kids * Psychosis section of Kiddie-SADS

Sponsors

Fondation Lenval
Lead SponsorOTHER

Study design

Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
DIAGNOSTIC
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
6 Years to 18 Years
Healthy volunteers
No

Inclusion criteria

* Twenty participants included with auditory hallucination: * Boy or girl * French * Over six years old and under eighteen years old * DSM-IV diagnosis of mood disorder, anxiety, disruptive behavioral disorder, attention deficit hyperactivity disorder, without schizophrenia diagnosis, without mental retardation (Intelligence Quotient (IQ)\>70), * Parental and child consent, affiliated to social security. * Twenty participants included without auditory hallucination: * Boy or girl * French, * Over six years old and under eighteen years old * DSM-IV diagnosis of mood disorder, anxiety, disruptive behavioral disorder, attention deficit hyperactivity disorder, without schizophrenia diagnosis, without mental retardation (IQ\>70) * Parental and child consent, affiliated to social security.

Exclusion criteria

* schizophrenia diagnosis, * neurologic, genetic or neurosensory disorders

Design outcomes

Primary

MeasureTime frameDescription
Evolution of the score of theory of mindChange from baseline 6 month laterThe social cognitive marker will be evaluate by NeuroPsychologic assessment NEPSY II for theory of mind

Secondary

MeasureTime frameDescription
Evolution of the score of Mental DisorderChange from baseline 6 month laterEvaluation of diagnosis of Mental Disorder with Diagnostic and Statistical Manual of Mental Disorders (DSM)-IV criteria using MINI-Kids (Mini International Neuropsychiatric Interview )
Evaluation of the score of PsychosisChange from baseline 6 month laterEvaluation of diagnosis of psychosis with DSM-IV (Diagnostic and Statistical Manual of Mental Disorders ) criteria using Psychosis section of Kiddie-SADS (Schedule for Affective Disorders and Schizophrenia for school age chidlren)
Evolution of the score of individual stabilityChange from baseline 6 month laterThe evaluation of the the emotional marker will be performed with the Differential emotion scale IV (DES IV): emotional individual stability
Evolution of the score of auditory hallucinations persistenceChange from baseline 6 month laterEvaluation of auditory hallucinations persistence with a self report scale using in recruiting criteria.
Evolution of auditory measure of patients' emotionalChange from baseline 6 month laterThe auditory measure will be performed by the score: The social cognitive marker (NEPSY II)
Evolution of Emotional real-life experience of the hallucinationChange from baseline 6 month laterThe Emotional real-life experience of the hallucination will be performed by the score: The Revised Beliefs About Voices Questionnaire (BAVQ-R)
Evolution of the score of affect recognitionChange from baseline 6 month laterThe social cognitive marker will be evaluate by NeuroPsychologic assessment NEPSY II for theory of affect recognition
Evolution of measure of recognition of the feelingsChange from baseline 6 month laterThe measure of recognition of the feelings will be performed by the score: The social cognitive marker (NEPSY II)

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 21, 2026