Obesity, Hypertension, Diabetes
Conditions
Brief summary
A trial testing the efficacy of sit-stand workstations on decreasing sitting time and increasing light-intensity physical activity in samples of office worksites.
Detailed description
With traditional approaches to increasing MVPA (moderate to vigorous physical activity) in the workplace being unsustainable due to the requirement of deliberate and dedicated time away from work, this group-randomized trial will test the efficacy of sit-stand workstations on decreasing sitting time and increasing light-intensity physical activity (LPA) in a highly generalizable sample of office worksites using a multi-level intervention with high potential for dissemination.
Interventions
DEVICESit-Stand workstation
Installation of a sit-stand desk at work
BEHAVIORALMove
A multi-level individual, social, environmental, and organizational intervention targeting increases in light-intensity physical activity in the workplace
Sponsors
University of Minnesota
Arizona State University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
Worksite-level inclusion criteria: * Size: Small to moderate size worksite (20-60 employees) * Schedule: \>80% of employees full time * Occupation: Seated office work, primarily computer- and- telephone-based work, little movement or walking * Wellness environment: Not currently undergoing a wellness program aimed at increasing activity at work * Workstations: Willing to have sit-stand workstations installed at a worksite * Willing to be randomized: Willing to be randomized to either intervention conditions Member-level inclusion criteria: * Age: 18 years and older * Health status: Generally good health and able to safely increase LPA and reduce sitting time * Employment status: Any sedentary job, sitting most of the say, little standing or walking * Occupation: Traditional sitting desk, willing to have a sit-stand workstation installed at desk * Workstation: traditional sitting desk;willing to have a sit-stand workstation installed at desk
Exclusion criteria
* contraindication to prolonged standing at work
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Mean Change in Light-intensity Physical Activity at Work From Baseline to 12 Months | 1 year | Measured via 7d of activPAL accelerometry (value at 12 months minus value at baseline) |
| Mean Change in Sitting Time at Work From Baseline to 12 Months | 1 year | Measured via 7d of activPAL accelerometry (value at 12 months minus value at baseline) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Clustered Metabolic Risk Score From Baseline to 12 Months | 1 year | Clustered metabolic risk score (fasting glucose, insulin, triglycerides, HDL-cholesterol, blood pressure); value at 12 months minus value at baseline; higher scores indicate better outcome. The Z-score for each component (fasting glucose, insulin, triglycerides, HDL-cholesterol, blood pressure) based on the baseline mean and standard deviation of the entire group was computed and summed for each participant (HDL z-score was subtracted rather than added). The sum of these z-scores represents the metabolic risk score. |
Other
| Measure | Time frame | Description |
|---|---|---|
| Sleep Substudy | 1 year | 24h wrist accelerometry in individuals with minor-moderate sleep complaints |
| Dynamic Glucose Control | 3 months | Continuous glucose monitoring in prediabetics |
| Ambulatory Blood Pressure | 3 months | Dynamic changes in ambulatory blood pressure in prehypertensives |
| Ecological Momentary Assessment of Mood | 1 year | Periodic monitoring of mood, energy, fatigue in smartphone users |
Countries
United States
Participant flow
Participants by arm
| Arm | Count |
|---|---|
| MOVE+ A multi-level individual, social, environmental, and organizational intervention targeting increases in light-intensity physical activity in the workplace.
Move: A multi-level individual, social, environmental, and organizational intervention targeting increases in light-intensity physical activity in the workplace | 276 |
| STAND+ Move intervention (A multi-level individual, social, environmental, and organizational intervention targeting increases in light-intensity physical activity in the workplace) plus the installation of a sit-stand workstation.
Sit-Stand workstation: Installation of a sit-stand desk at work
Move: A multi-level individual, social, environmental, and organizational intervention targeting increases in light-intensity physical activity in the workplace | 354 |
| Total | 630 |
Baseline characteristics
| Characteristic | Total | MOVE+ | STAND+ |
|---|---|---|---|
| Age, Categorical <=18 years | 0 Participants | 0 Participants | 0 Participants |
| Age, Categorical >=65 years | 0 Participants | 0 Participants | 0 Participants |
| Age, Categorical Between 18 and 65 years | 630 Participants | 276 Participants | 354 Participants |
| Age, Continuous | 45 years STANDARD_DEVIATION 11 | 44 years STANDARD_DEVIATION 11 | 47 years STANDARD_DEVIATION 11 |
| Race/Ethnicity, Customized Hispanic | 87 Participants | 30 Participants | 57 Participants |
| Race/Ethnicity, Customized Non-Hispanic Asian | 32 Participants | 17 Participants | 15 Participants |
| Race/Ethnicity, Customized Non-Hispanic Black | 26 Participants | 6 Participants | 20 Participants |
| Race/Ethnicity, Customized Non-Hispanic White | 489 Participants | 250 Participants | 239 Participants |
| Race/Ethnicity, Customized Other/Multiracial/Unknown | 41 Participants | 18 Participants | 23 Participants |
| Region of Enrollment United States | 630 participants | 276 participants | 354 participants |
| Sex: Female, Male Female | 469 Participants | 173 Participants | 296 Participants |
| Sex: Female, Male Male | 161 Participants | 103 Participants | 58 Participants |
Adverse events
| Event type | EG000 affected / at risk | EG001 affected / at risk |
|---|---|---|
| deaths Total, all-cause mortality | 0 / 276 | 0 / 354 |
| other Total, other adverse events | 0 / 276 | 0 / 354 |
| serious Total, serious adverse events | 0 / 276 | 0 / 354 |
Outcome results
Primary
Mean Change in Light-intensity Physical Activity at Work From Baseline to 12 Months
Measured via 7d of activPAL accelerometry (value at 12 months minus value at baseline)
Time frame: 1 year
Population: Among those who completed the study in the MOVE+ arm (n=247), 16 did not have sufficient valid workdays and 7 were missing covariates. Among those who completed the study in the STAND+ arm (n=292), 17 did not have sufficient valid workdays and 12 were missing covariates.
| Arm | Measure | Value (MEAN) |
|---|---|---|
| MOVE+ | Mean Change in Light-intensity Physical Activity at Work From Baseline to 12 Months | -0.2 Mean change, minutes per 8hr workday |
| STAND+ | Mean Change in Light-intensity Physical Activity at Work From Baseline to 12 Months | 2.0 Mean change, minutes per 8hr workday |
Primary
Mean Change in Sitting Time at Work From Baseline to 12 Months
Measured via 7d of activPAL accelerometry (value at 12 months minus value at baseline)
Time frame: 1 year
Population: Among those who completed the study in the MOVE+ arm (n=247), 16 did not have sufficient valid workdays and 7 were missing covariates. Among those who completed the study in the STAND+ arm (n=292), 17 did not have sufficient valid workdays and 12 were missing covariates.
| Arm | Measure | Value (MEAN) |
|---|---|---|
| MOVE+ | Mean Change in Sitting Time at Work From Baseline to 12 Months | 6.8 Mean Change, minutes per 8h workday |
| STAND+ | Mean Change in Sitting Time at Work From Baseline to 12 Months | -52.4 Mean Change, minutes per 8h workday |
Secondary
Clustered Metabolic Risk Score From Baseline to 12 Months
Clustered metabolic risk score (fasting glucose, insulin, triglycerides, HDL-cholesterol, blood pressure); value at 12 months minus value at baseline; higher scores indicate better outcome. The Z-score for each component (fasting glucose, insulin, triglycerides, HDL-cholesterol, blood pressure) based on the baseline mean and standard deviation of the entire group was computed and summed for each participant (HDL z-score was subtracted rather than added). The sum of these z-scores represents the metabolic risk score.
Time frame: 1 year
Population: In MOVE+ (n=247), 10 did not attend posttest visit, 3 were unable to perform a blood draw, 19 refused blood draw, 3 had an insufficent sample, and 8 were missing covariates. In STAND+ (n=292), 16 did not attend posttest visit, 3 were unable to perform a blood draw, 27 refused blood draw, 3 had an insufficent sample, and 5 were missing covariates.
| Arm | Measure | Value (MEAN) |
|---|---|---|
| MOVE+ | Clustered Metabolic Risk Score From Baseline to 12 Months | 0.02 units on a scale |
| STAND+ | Clustered Metabolic Risk Score From Baseline to 12 Months | -0.15 units on a scale |
Other Pre-specified
Ambulatory Blood Pressure
Dynamic changes in ambulatory blood pressure in prehypertensives
Time frame: 3 months
Other Pre-specified
Dynamic Glucose Control
Continuous glucose monitoring in prediabetics
Time frame: 3 months
Other Pre-specified
Ecological Momentary Assessment of Mood
Periodic monitoring of mood, energy, fatigue in smartphone users
Time frame: 1 year
Other Pre-specified
Sleep Substudy
24h wrist accelerometry in individuals with minor-moderate sleep complaints
Time frame: 1 year