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I-gel Versus Classic-Laryngeal Mask Airway (C-LMA) as a Conduit for Tracheal Intubation Using Ventilating Bougie

I-gel Versus C-LMA as a Conduit for Tracheal Intubation Using Ventilating Bougie

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02566135
Enrollment
58
Registered
2015-10-02
Start date
2014-03-31
Completion date
2015-02-28
Last updated
2018-07-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intubation; Difficult

Keywords

C-LMA, I-gel, ventilating bougie, intubation

Brief summary

Supraglottic Airway devices(SGAs) like I-Gel and C-LMA ( classic laryngeal mask airway ) have been used as a conduit for tracheal intubation using ventilating bougie. General Anaesthesia with tracheal intubation is one of the technique for giving anaesthesia. Tracheal intubation may become difficult sometimes and endangers patients life. Using SGAs as a conduit for tracheal intubation helps in securing airway. This will be further facilitated by using ventilating bougie, as it maintains oxygenation.

Detailed description

SGAs have been used as a conduit for tracheal intubation using ventilating bougie. Patients were anaesthetised with intravenous induction agent, non-depolarising muscle relaxant and then SGAs were inserted. Two groups were compared. In group I : I-gel was inserted, its position was confirmed and then ventilating bougie was inserted through it. It's position was confirmed, then I-gel was removed , Endotracheal tube was railroaded over ventilating bougie and it's position was confirmed. In group C : C-LMA was inserted, its position was confirmed and then ventilating bougie was inserted through it. It's position was confirmed, then C-LMA was removed , Endotracheal tube was railroaded over ventilating bougie and it's position was confirmed.

Interventions

DEVICETracheal Intubation using I-gel and ventilating bougie

Following general anaesthesia I-gel was inserted. After proper placement . ventilating bougie was inserted. Once it's placement is confirmed I-gel was removed keeping the ventilating bougie in situ. Then appropriate sized endotracheal tube was railroaded over ventilating bougie then it (v.bouggie) was removed . Proper placement of endotracheal tube was confirmed by bilateral equal chest excursion and air entry on auscultation, absence of gastric insuffflation sound over epigastrium and 'sine' wave on capnography. Maximum 3 attempts were allowed for I-gel, ventilating bougie and endotracheal tube.

DEVICETracheal Intubation using C-LMA and ventilating bougie

Following general anaesthesia C-LMA was inserted. After proper placement of C-LMA, ventilating bougie was inserted. It's placement was confirmed and C-LMA was removed after deflation of cuff keeping the ventilating bougie in situ. Then appropriate sized endotracheal tube was railroaded over ventilating bougie. It's placement was confirmed by bilateral equal air entry and chest excursion, absence of gastric insufflation sound over epigastrium and 'sine' wave on capnography. Maximum 3 attempts were allowed for C-LMA , ventilating bougie and endotracheal tube.

Sponsors

Medical College Baroda
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
Yes

Inclusion criteria

* age 18 to 60 years * Gender : either sex * American society of Anaesthesiologist's Physical Status (ASAPS) I and II * Patients posted for surgery requiring general anaesthesia and endotracheal intubation.

Exclusion criteria

* age \<18 years and \> 60 years * ASAPS III or IV * Obesity body mass index \>25 * Patients with mouth opening \<2cms * Patients with Malampatti grade III and IV * Patients having history of gastro-esophageal reflux disease * Patients with history of inadequate fasting * Patients with known or anticipated difficult tracheal intubation or face-mask ventilation.

Design outcomes

Primary

MeasureTime frame
Total Intubation Time5 minutes
Number of Attempts for Ventilating Bougie Insertions Through I-gel or C-LMA45 seconds
Number of Attempts for Railroading of Endotracheal Tube Over Ventilating Bougie30 seconds
Time of Insertion5 minutes
Number of Attempts for I-gel or Classic-LMA Insertions60 seconds

Secondary

MeasureTime frameDescription
Systolic Blood Pressure25 minutesSystolic blood pressure measured at following time intervals. 1. Base line 2. After Dexmedetomidine injection 3. After induction of anaesthesia 4. Supraglottic airway insertion 5. Ventilating bougie insertion 6. ETT insertion 7. 3 minute after ETT insertion 8. 5 minute after ETT insertion 9. 7 minute after ETT insertion 10. 10 minute after ETT insertion 11. 15 minute after ETT insertion. The study period was upto 15 minutes and thereafter the study ends.
Diastolic Blood Pressure25 minutesDiastolic blood pressure measured at following time intervals. 1. Base line 2. After Dexmedetomidine injection 3. After Induction 4. Supraglottic airway insertion 5. Ventilating bougie insertion 6. ETT insertion 7. 3 minute after ETT insertion 8. 5 minute after ETT insertion 9. 7 minute after ETT insertion 10. 10 minutes after ETT insertion 11. 15 minute after ETT insertion The study period was upto 15 minutes. thereafter study ends.
Heart Rate25 minutesHeart rate to observe at the following time intervals. 1. Base line 2. After induction 3. After dexmedetomidine injection 4. Supraglottic airway insertion 5. Ventilating bougie insertion 6. ETT insertion 7. 3minute after ETT insertion 8. 5 minute after ETT insertion 9. 7 minute after ETT insertion 10. 10 minute after ETT insertion 11. 15 minute after ETT insertion Study period is upto 15 minutes, thereafter the study ends here.

Participant flow

Participants by arm

ArmCount
Group-I
In Group-I, I-gel is to be used as a conduit for tracheal intubation using ventilating bougie. Tracheal Intubation: Following general anaesthesia I-gel was inserted. After proper placement . ventilating bougie was inserted. Once it's placement is confirmed I-gel was removed keeping the ventilating bougie in situ. Then appropriate sized endotracheal tube was railroaded over ventilating bougie then it (v.bouggie) was removed . Proper placement of endotracheal tube was confirmed by bilateral equal chest excursion and air entry on auscultation, absence of gastric insuffflation sound over epigastrium and 'sine' wave on capnography. Maximum 3 attempts were allowed for I-gel, ventilating bougie and endotracheal tube.
29
Group-C
In Group-C, C-LMA is to be used as a conduit for tracheal intubation using ventilating bougie. Tracheal Intubation: Following general anaesthesia C-LMA was inserted. Aftre proper placement ventilating bougie was inserted. It's placement was confirmed and C-LMA was removed after deflation of cuff keeping the ventilating bougie in situ. Then appropriate sized endotracheal tube was railroaded over ventilating bougie. It's placement was confirmed by bilateral equal air entry and chest excursion, absence of gastric insufflation sound over epigastrium and 'sine' wave on capnography. Maximum 3 attempts were allowed for C-LMA , ventilating bougie and endotracheal tube.
29
Total58

Baseline characteristics

CharacteristicGroup-IGroup-CTotal
Age, Categorical
<=18 years
0 Participants0 Participants0 Participants
Age, Categorical
>=65 years
0 Participants0 Participants0 Participants
Age, Categorical
Between 18 and 65 years
29 Participants29 Participants58 Participants
Age, Continuous35.03 Years
STANDARD_DEVIATION 10.13
36.13 Years
STANDARD_DEVIATION 11.24
35.58 Years
STANDARD_DEVIATION 10.68
ASAPS ( American society of Anaesthesiologist's physical ststus
ASAPS I
21 participants23 participants44 participants
ASAPS ( American society of Anaesthesiologist's physical ststus
ASAPS II
8 participants6 participants14 participants
BMI (body mass index)21.30 Kg/m2
STANDARD_DEVIATION 2.96
21.43 Kg/m2
STANDARD_DEVIATION 2.19
21.36 Kg/m2
STANDARD_DEVIATION 2.57
Sex: Female, Male
Female
13 Participants15 Participants28 Participants
Sex: Female, Male
Male
16 Participants14 Participants30 Participants

Adverse events

Event typeEG000
affected / at risk
EG001
affected / at risk
deaths
Total, all-cause mortality
— / —— / —
other
Total, other adverse events
2 / 294 / 29
serious
Total, serious adverse events
0 / 290 / 29

Outcome results

Primary

Number of Attempts for I-gel or Classic-LMA Insertions

Time frame: 60 seconds

ArmMeasureGroupValue (NUMBER)
Group-INumber of Attempts for I-gel or Classic-LMA Insertions1st attempt25 attempt
Group-INumber of Attempts for I-gel or Classic-LMA Insertions2nd attempt2 attempt
Group-INumber of Attempts for I-gel or Classic-LMA Insertions3rd attempt2 attempt
Group-CNumber of Attempts for I-gel or Classic-LMA Insertions1st attempt22 attempt
Group-CNumber of Attempts for I-gel or Classic-LMA Insertions2nd attempt5 attempt
Group-CNumber of Attempts for I-gel or Classic-LMA Insertions3rd attempt2 attempt
Comparison: Chi square test was applied to see weather there is a statistical significant difference between group I and group C for attempt for supraglottic airway insertion.p-value: 0.503395% CI: [0.6401, 3.3428]Chi-squared, Corrected
Primary

Number of Attempts for Railroading of Endotracheal Tube Over Ventilating Bougie

Time frame: 30 seconds

ArmMeasureGroupValue (NUMBER)
Group-INumber of Attempts for Railroading of Endotracheal Tube Over Ventilating Bougie1st attempt29 attempt
Group-INumber of Attempts for Railroading of Endotracheal Tube Over Ventilating Bougie2nd attempt0 attempt
Group-INumber of Attempts for Railroading of Endotracheal Tube Over Ventilating Bougie3rd attempt0 attempt
Group-CNumber of Attempts for Railroading of Endotracheal Tube Over Ventilating Bougie1st attempt28 attempt
Group-CNumber of Attempts for Railroading of Endotracheal Tube Over Ventilating Bougie2nd attempt1 attempt
Group-CNumber of Attempts for Railroading of Endotracheal Tube Over Ventilating Bougie3rd attempt0 attempt
p-value: >0.05Chi-squared, Corrected
Primary

Number of Attempts for Ventilating Bougie Insertions Through I-gel or C-LMA

Time frame: 45 seconds

ArmMeasureGroupValue (NUMBER)
Group-INumber of Attempts for Ventilating Bougie Insertions Through I-gel or C-LMA1st attempt23 attempt
Group-INumber of Attempts for Ventilating Bougie Insertions Through I-gel or C-LMA2nd attempt6 attempt
Group-INumber of Attempts for Ventilating Bougie Insertions Through I-gel or C-LMA3rd attempt0 attempt
Group-CNumber of Attempts for Ventilating Bougie Insertions Through I-gel or C-LMA1st attempt24 attempt
Group-CNumber of Attempts for Ventilating Bougie Insertions Through I-gel or C-LMA2nd attempt4 attempt
Group-CNumber of Attempts for Ventilating Bougie Insertions Through I-gel or C-LMA3rd attempt1 attempt
Comparison: We had applied chi square to see the statistical significant difference between group I and group C for number of attempt for ventilating bougie insertion.p-value: >0.0595% CI: [0.4858, 1.6569]Chi-squared, Corrected
Primary

Time of Insertion

Time frame: 5 minutes

ArmMeasureGroupValue (MEAN)Dispersion
Group-ITime of InsertionSupraglottic airway26.17 SecondsStandard Deviation 2.25
Group-ITime of InsertionVentilating bougie31.51 SecondsStandard Deviation 8.87
Group-ITime of InsertionETT25.58 SecondsStandard Deviation 4.01
Group-CTime of InsertionSupraglottic airway44.65 SecondsStandard Deviation 9.14
Group-CTime of InsertionVentilating bougie26.31 SecondsStandard Deviation 9.25
Group-CTime of InsertionETT28.13 SecondsStandard Deviation 8.31
Comparison: We had compared time of insertion for supraglottic airway between group I and group C.p-value: <0.0001t-test, 2 sided
Primary

Total Intubation Time

Time frame: 5 minutes

ArmMeasureValue (MEAN)Dispersion
Group-ITotal Intubation Time93.27 SecondStandard Deviation 9.03
Group-CTotal Intubation Time108.96 SecondStandard Deviation 16.5
p-value: <0.0001t-test, 2 sided
Secondary

Diastolic Blood Pressure

Diastolic blood pressure measured at following time intervals. 1. Base line 2. After Dexmedetomidine injection 3. After Induction 4. Supraglottic airway insertion 5. Ventilating bougie insertion 6. ETT insertion 7. 3 minute after ETT insertion 8. 5 minute after ETT insertion 9. 7 minute after ETT insertion 10. 10 minutes after ETT insertion 11. 15 minute after ETT insertion The study period was upto 15 minutes. thereafter study ends.

Time frame: 25 minutes

ArmMeasureGroupValue (MEAN)Dispersion
Group-IDiastolic Blood PressureETT insertion76.51 mmhgStandard Deviation 5.19
Group-IDiastolic Blood Pressure3 min after ETT insertion76.24 mmhgStandard Deviation 4.04
Group-IDiastolic Blood PressureBaseline79.96 mmhgStandard Deviation 5.88
Group-IDiastolic Blood Pressure5 min after ETT insertion76.03 mmhgStandard Deviation 4.38
Group-IDiastolic Blood PressureSGA insertion75.24 mmhgStandard Deviation 5.13
Group-IDiastolic Blood Pressure7 min after ETT insertion76.1 mmhgStandard Deviation 4.38
Group-IDiastolic Blood PressureAfter Dex injection71.24 mmhgStandard Deviation 7.67
Group-IDiastolic Blood Pressure10 min after ETT insertion77.37 mmhgStandard Deviation 3.6
Group-IDiastolic Blood PressureV. Bougie insertion77.03 mmhgStandard Deviation 4.22
Group-IDiastolic Blood Pressure15 min after ETT insertion77.1 mmhgStandard Deviation 4.35
Group-IDiastolic Blood PressureAfter induction70.1 mmhgStandard Deviation 7.99
Group-CDiastolic Blood Pressure15 min after ETT insertion76.79 mmhgStandard Deviation 5.48
Group-CDiastolic Blood PressureAfter Dex injection73.68 mmhgStandard Deviation 9.03
Group-CDiastolic Blood PressureBaseline81.51 mmhgStandard Deviation 6.57
Group-CDiastolic Blood PressureAfter induction72.79 mmhgStandard Deviation 8.64
Group-CDiastolic Blood PressureSGA insertion75.17 mmhgStandard Deviation 8.37
Group-CDiastolic Blood PressureV. Bougie insertion76.51 mmhgStandard Deviation 6.4
Group-CDiastolic Blood Pressure3 min after ETT insertion75.34 mmhgStandard Deviation 5.72
Group-CDiastolic Blood Pressure5 min after ETT insertion75.03 mmhgStandard Deviation 6.57
Group-CDiastolic Blood Pressure7 min after ETT insertion75.72 mmhgStandard Deviation 5.22
Group-CDiastolic Blood Pressure10 min after ETT insertion76.79 mmhgStandard Deviation 6.96
Group-CDiastolic Blood PressureETT insertion75.68 mmhgStandard Deviation 5.5
Comparison: Diastolic blood pressure measured and compared at base line between group I and group C.p-value: 0.34t-test, 2 sided
Comparison: Diastolic blood pressure measured and compared following Dexmedetomidine injection between group I and group C.p-value: 0.27t-test, 2 sided
Comparison: Diastolic blood pressure measured and compared following induction of anaesrthesia between group I and group C.p-value: 0.22t-test, 2 sided
Comparison: Diastolic blood pressure measured and compared following supraglottic airway insertion between group I and group C.p-value: 0.96t-test, 2 sided
Comparison: Diastolic blood pressure measured and compared following ventilating bougie insertion between group I and group C.p-value: 0.71t-test, 2 sided
Comparison: Diastolic blood pressure measured and compared the time of endotracheal tube insertion between group I and group C.p-value: 0.55t-test, 2 sided
Comparison: Diastolic blood pressure measured and compared 3 minutes after endotracheal tube insertion between group I and group C.p-value: 0.49t-test, 2 sided
Comparison: Diastolic blood pressure measured and compared 5 minutes after endotracheal tube insertion between group I and group C.p-value: 0.49t-test, 2 sided
Comparison: Diastolic blood pressure measured and compared 7 minutes after endotracheal tube insertion between group I and group C.p-value: 0.76t-test, 2 sided
Comparison: Diastolic blood pressure measured and compared 10 minutes after endotracheal tube insertion between group I and group C.p-value: 0.69t-test, 2 sided
Comparison: Diastolic blood pressure measured and compared 15 minutes after endotracheal tube insertion between group I and group C.p-value: 0.81t-test, 2 sided
Secondary

Heart Rate

Heart rate to observe at the following time intervals. 1. Base line 2. After induction 3. After dexmedetomidine injection 4. Supraglottic airway insertion 5. Ventilating bougie insertion 6. ETT insertion 7. 3minute after ETT insertion 8. 5 minute after ETT insertion 9. 7 minute after ETT insertion 10. 10 minute after ETT insertion 11. 15 minute after ETT insertion Study period is upto 15 minutes, thereafter the study ends here.

Time frame: 25 minutes

ArmMeasureGroupValue (MEAN)Dispersion
Group-IHeart RateETT insertion83.27 beats per minuteStandard Deviation 9.75
Group-IHeart Rate3 min after ETT insertion83.75 beats per minuteStandard Deviation 8.78
Group-IHeart RateAfter Dex injection71.24 beats per minuteStandard Deviation 9.98
Group-IHeart Rate5 min after ETT insertion81.17 beats per minuteStandard Deviation 6.99
Group-IHeart RateSGA insertion75.68 beats per minuteStandard Deviation 9.41
Group-IHeart Rate7 min after ETT insertion81.86 beats per minuteStandard Deviation 7.01
Group-IHeart RateBaseline91.06 beats per minuteStandard Deviation 11.72
Group-IHeart Rate10 min after ETT insertion80.86 beats per minuteStandard Deviation 6.53
Group-IHeart RateV. Bougie insertion85.55 beats per minuteStandard Deviation 6.6
Group-IHeart Rate15 min after ETT insertion81.13 beats per minuteStandard Deviation 5.87
Group-IHeart RateAfter induction69.87 beats per minuteStandard Deviation 11.81
Group-CHeart Rate15 min after ETT insertion78.41 beats per minuteStandard Deviation 8.02
Group-CHeart RateBaseline88.89 beats per minuteStandard Deviation 9.76
Group-CHeart RateAfter Dex injection72.75 beats per minuteStandard Deviation 10.76
Group-CHeart RateAfter induction74.1 beats per minuteStandard Deviation 11.17
Group-CHeart RateSGA insertion78.79 beats per minuteStandard Deviation 9.73
Group-CHeart RateV. Bougie insertion82.41 beats per minuteStandard Deviation 5.78
Group-CHeart Rate3 min after ETT insertion82.72 beats per minuteStandard Deviation 7.65
Group-CHeart Rate5 min after ETT insertion79 beats per minuteStandard Deviation 8.62
Group-CHeart Rate7 min after ETT insertion79.34 beats per minuteStandard Deviation 7.31
Group-CHeart Rate10 min after ETT insertion78.79 beats per minuteStandard Deviation 6.39
Group-CHeart RateETT insertion81.65 beats per minuteStandard Deviation 5.94
Comparison: Heart rate beats per minute measured at base line among the group I and group C.p-value: 0.44t-test, 2 sided
Comparison: Heart rate beats per minute is measured following Dexmedetomidine injection among the group I and group C.p-value: 0.58t-test, 2 sided
Comparison: Heart rate beats per minute measured following induction of anaesthesia among the group I and group C.p-value: 0.16t-test, 2 sided
Comparison: Heart rate beats per minute measured following supraglottic airway insertion among the group I and group C.p-value: 0.22t-test, 2 sided
Comparison: Heart rate beats per minute measured following ventilating bougie insertion among the group I and group C.p-value: 0.059t-test, 2 sided
Comparison: Heart rate beats per minute measured at endotracheal intubation among the group I and group C.p-value: >0.33t-test, 2 sided
Comparison: Heart rate beats per minute measured after 3 minute of ETT insertion among the group I and group C.p-value: 0.63t-test, 2 sided
Comparison: Heart rate beats per minute measured after 5 minute of ETT insertion among the group I and group C.p-value: 0.29t-test, 2 sided
Comparison: Heart rate beats per minute measured after 7 minute of ETT insertion among the group I and group C.p-value: 0.18t-test, 2 sided
Comparison: Heart rate beats per minute measured after 10 minute of ETT insertion among the group I and group C.p-value: 0.98t-test, 2 sided
Comparison: Heart rate beats per minute measured after 15 minute of ETT insertion among the group I and group C.p-value: 0.49t-test, 2 sided
Secondary

Systolic Blood Pressure

Systolic blood pressure measured at following time intervals. 1. Base line 2. After Dexmedetomidine injection 3. After induction of anaesthesia 4. Supraglottic airway insertion 5. Ventilating bougie insertion 6. ETT insertion 7. 3 minute after ETT insertion 8. 5 minute after ETT insertion 9. 7 minute after ETT insertion 10. 10 minute after ETT insertion 11. 15 minute after ETT insertion. The study period was upto 15 minutes and thereafter the study ends.

Time frame: 25 minutes

ArmMeasureGroupValue (MEAN)Dispersion
Group-ISystolic Blood PressureSGA insertion113.93 mmhgStandard Deviation 6.14
Group-ISystolic Blood Pressure3 min after ETT insertion116.03 mmhgStandard Deviation 4.91
Group-ISystolic Blood PressureBaseline122.31 mmhgStandard Deviation 8.07
Group-ISystolic Blood Pressure5 min after ETT insertion118.62 mmhgStandard Deviation 5.36
Group-ISystolic Blood PressureV. Bougie insertion118.65 mmhgStandard Deviation 5.17
Group-ISystolic Blood Pressure7 min after ETT insertion115.13 mmhgStandard Deviation 5.35
Group-ISystolic Blood PressureAfter Dex injection109.96 mmhgStandard Deviation 8.15
Group-ISystolic Blood Pressure10 min after ETT insertion116.93 mmhgStandard Deviation 6.55
Group-ISystolic Blood PressureETT insertion117.37 mmhgStandard Deviation 4.87
Group-ISystolic Blood Pressure15 min after ETT insertion116.62 mmhgStandard Deviation 6.61
Group-ISystolic Blood PressureAfter induction108.03 mmhgStandard Deviation 8.34
Group-CSystolic Blood Pressure15 min after ETT insertion118.1 mmhgStandard Deviation 9.54
Group-CSystolic Blood PressureBaseline125.31 mmhgStandard Deviation 11.06
Group-CSystolic Blood PressureAfter Dex injection114.34 mmhgStandard Deviation 12.41
Group-CSystolic Blood PressureAfter induction112.51 mmhgStandard Deviation 10.53
Group-CSystolic Blood PressureSGA insertion114.24 mmhgStandard Deviation 6.62
Group-CSystolic Blood PressureV. Bougie insertion116.10 mmhgStandard Deviation 4.73
Group-CSystolic Blood PressureETT insertion117.93 mmhgStandard Deviation 6.7
Group-CSystolic Blood Pressure3 min after ETT insertion118.31 mmhgStandard Deviation 8.1
Group-CSystolic Blood Pressure5 min after ETT insertion118.31 mmhgStandard Deviation 8.1
Group-CSystolic Blood Pressure7 min after ETT insertion115.79 mmhgStandard Deviation 6.95
Group-CSystolic Blood Pressure10 min after ETT insertion116.96 mmhgStandard Deviation 10.95
Comparison: Systolic blood pressure measured and compared at base line between group I and group C.p-value: 0.24t-test, 2 sided
Comparison: Systolic blood pressure measured and compared following Dexmedetomidine injection between group I and group C.p-value: 0.11t-test, 2 sided
Comparison: Systolic blood pressure measured and compared following induction os anaesthesia between group I and group C.p-value: 0.07t-test, 2 sided
Comparison: Systolic blood pressure measured and compared following supraglottic airway insertion between group I and group C.p-value: 0.85t-test, 2 sided
Comparison: Systolic blood pressure measured and compared following ventilating bougie insertion between group I and group C.p-value: 0.055t-test, 2 sided
Comparison: Systolic blood pressure measured and compared at ETT insertion time between group I and group C.p-value: 0.71t-test, 2 sided
Comparison: Systolic blood pressure measured and compared 3 minutes after ETT insertion between group I and group C.p-value: 0.2t-test, 2 sided
Comparison: Systolic blood pressure measured and compared 5 minutes after ETT insertion between group I and group C.p-value: 0.86t-test, 2 sided
Comparison: Systolic blood pressure measured and compared 7 minutes after ETT insertion between group I and group C.p-value: 0.68t-test, 2 sided
Comparison: Systolic blood pressure measured and compared 10 minutes after ETT insertion between group I and group C.p-value: 0.98t-test, 2 sided
Comparison: Systolic blood pressure measured and compared 15 minutes after ETT insertion between group I and group C.p-value: 0.49t-test, 2 sided

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026