Bronchiectasis
Conditions
Keywords
children, prognosis
Brief summary
This prospective cohort study is designed to observe of the effect of intervention therapy on the long-term prognosis of children with bronchiectasis. The main purpose of the study was to evaluate the degree of deterioration of lung function, to observe and compare the quality of life, the time of pulmonary exacerbation, and the changes of lung image.
Detailed description
All enrolled patients are followed up for half a year, 1 years, 2 years, 3 years, 4 years, 5 years, while observation of pulmonary function, symptoms, signs, quality of life, the times of acute pulmonary exacerbation, and the changes of lung image are performed.
Interventions
None listed
Sponsors
Wuhan women and children's health care center
Children's Hospital of Chongqing Medical University
Yuying Children's Hospital of Wenzhou Medical University
Changchun Children's Hospital
Shenzhen Children's Hospital
Jiangxi Province Children's Hospital
Shanghai Children's Medical Center
First Affiliated Hospital of Guangxi Medical University
Tianjin Children's Hospital
The First Affiliated Hospital of Xiamen University
Children's Hospital of Fudan University
The Affiliated Hospital Of Guizhou Medical University
Shanxi Provincial Maternity and Children's Hospital
Baoping XU
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
No minimum to 18 Years
Healthy volunteers
No
Inclusion criteria
A included patient must be coincident at least one point of the four items of high-resolution computed tomography (HRCT) manifestations. * Internal bronchial diameter greater than the accompanying pulmonary artery. * lack of bronchial tapering * bronchi visible in the peripheral 1cm of lung * bronchial diameter greater than adjacent segmental bronchi
Exclusion criteria
Subject will be excluded if she or he has one of the following * It is unable or doesn't agree to accept the follow-up process * undergoing trial for other medications or instruments.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change from baseline in lung function on the spirometry | 5 years | forced expiratory volume at one second (FEV1) in Liter |
Countries
China
Contacts
Primary ContactBaoping Xu, MD,PhD
Outcome results
None listed