Comparison of Hemodynamic Changes by Using the Videolaryngoscope and the Macintosh Laryngoscope

Comparison of Hemodynamic Changes After Endotracheal Intubation by Using the Videolaryngoscope and the Macintosh Direct Laryngoscope in Elderly Hypertensive Patients

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02564640

Enrollment

100

Registered

2015-10-01

Start date

2015-06-30

Completion date

2015-09-30

Last updated

2015-12-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anesthesia Intubation Complication

Keywords

videolaryngoscope, direct laryngoscope, hemodynamic changes, elderly patients

Brief summary

Tracheal intubation techniques that avoid or minimize pharyngolaryngeal stimulation might attenuate the hemodynamic stress response. Tracheal intubation using video laryngoscope needs comparatively less airway manipulation so, the investigators expect less hemodynamic response while using videolaryngoscope.

Detailed description

The hemodynamic stress response to tracheal intubation can precipitate adverse cardiovascular events in patients with cardiovascular disease. Which is shown to greatly increase the risk of myocardial infarction or stroke, especially in elderly patients with hypertension. Direct laryngoscopy and laryngoscopic stimulation of pharyngolaryngeal structures may be an important factor in the hemodynamic stress response associated with tracheal intubation. Patients were randomly allocated to two groups using a permuted block randomization method: 1) patients intubated by using the videolaryngoscopy 2) patients intubated by using the Macintosh laryngoscope . SAP, MAP, and heart rate were measured and recorded in the operating room: At baseline, before intubation, immediately after intubation and 1,2,3,4 and 5 minutes after tracheal intubation.

Interventions

DEVICEvideolaryngoscope

patients intubated by using the videolaryngoscope

DEVICEMacintosh laryngoscope

patients intubated by using the Macintosh laryngoscope

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

65 Years to 90 Years

Healthy volunteers

Inclusion criteria

* American Society of Anesthesiologists Physical Status II-III, * aged over 65 years, * controlled hypertensive patients, * scheduled for elective coronary artery bypass grafting.

Exclusion criteria

* American Society of Anesthesiologists Physical Status IV, * ejection fraction \< 40%, * any anatomical abnormality in head, neck or face, * Mallampati score of IV, * history of difficult intubation or laryngoscopy

Design outcomes

Primary

Measure	Time frame
Blood pressure changes during tracheal intubation ( mmHg ) ,	At baseline, 1 minute before intubation, and 1,2,3,4 and 5 minutes after tracheal intubation

Secondary

Measure	Time frame	Description
Heart rate changes during tracheal intubation (beats per minute)	At baseline, 1 minute before intubation, and 1,2,3,4 and 5 minutes after tracheal intubation	—
ST segment elevation in electrocardiogram indicating myocardial ischaemia during tracheal intubation	At baseline, 1 and 5 minutes after tracheal intubation.	During tracheal intubation electrocardiogram is monitorized.
Arrhythmic changes in electrocardiogram during tracheal intubation	At baseline, 1 and 5 minutes after tracheal intubation.	During tracheal intubation electrocardiogram is monitorized.

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026