Coronary Artery Aneurysm Registry

Conditions

Coronary Artery Aneurysm

Keywords

coronary artery aneurysm, prognosis, outcomes, management, incidence, heart failure, acute coronary syndrome, death

Brief summary

International registry gathering patients with angiographically confirmed coronary aneurysm.

Detailed description

INTRODUCTION AND RATIONALE: Coronary artery aneurysm is defined as coronary dilatation which exceeds the diameter of normal adjacent segments or the diameter of the patient's largest coronary vessel by 1.5 times. Described by Bourgon, it is an uncommon disease which has been diagnosed with increasing frequency since the advent of coronary angiography. The incidence varies from 1.5% to 5% with male dominance and a predilection for the right coronary artery. Although several causes have been reported, atherosclerosis accounts for 50% of coronary aneurysms in adults. Reported complications include thrombosis and distal embolization, rupture and vasospasm, causing ischemia, heart failure or arrhythmias. The natural history and prognosis remains obscure, since definitive data are scarce. Controversies persist regarding the use of medical management (antithrombotic) or interventional/surgical procedures. OBJECTIVES. Taking into account the classical coronary aneurysm definition, the investigators propose: * ANATOMIC OBJECTIVES. * To characterize coronary aneurysms frequency over all cause invasive coronary angiography. * To describe anatomy, location and aneurysms features. * To assess intracoronary imaging data if available. * To describe the natural history, when evolutive chats were available * CLINICAL OBJECTIVES. * Cause for the diagnostic catheterization and aneurysms symptoms, if present. * Patient´s clinical features. * Long-term outcomes. * THERAPEUTIC OBJECTIVES. * To assess management strategies, conservative, interventional or surgical and its short and long term results. * Outcomes regarding management. DESIGN: * Retrospective recruitment, prospective follow-up registry. * Multicentric/international. * Anonymized. * Electronic database. Centralized analysis (core) at Hospital Clínico San Carlos. * Recruitment: 1/january/2002-1/december/2015.

Sánchez-Sánchez I, Cerrato E, Bollati M, Espejo-Paeres C, Nombela-Franco L, Alfonso-Rodríguez E, Camacho-Freire SJ, Villablanca PA, Amat-Santos IJ, De la Torre Hernández JM, Pascual I, Liebetrau C, Camacho B, Pavani M, Albistur J, Latini RA, Varbella F, Jiménez Díaz VA, Piraino D, Mancone M, Alfonso F, Linares JA, Rodríguez-Olivares R, Jiménez-Mazuecos JM, Palazuelos Molinero J, Sánchez-Grande Flecha A, Gomez-Hospital JA, Ielasi A, Lozano Í, Omedè P, Feltes G, Ugo F, Medda M, Ramakrishna H, Kala P, Bautista D, Alkhouli M, Fernández-Ortiz A, Núñez-Gil IJ, CAAR Investigators.

2024-11-016 citations

10.1016/j.jcin.2024.08.034

Sex differences in treatment strategy for coronary artery aneurysms: Insights from the international Coronary Artery Aneurysm Registry.

Arslan F, Núñez-Gil IJ, Rodríguez-Olivares R, Cerrato E, Bollati M, Nombela-Franco L, Terol B, Alfonso-Rodríguez E, Camacho Freire SJ, Villablanca PA, Amat Santos IJ, De la Torre Hernández JM, Pascual I, Liebetrau C, Alkhouli M, Fernández-Ortiz A, Coronary Artery Aneurysm Registry (CAAR) investigators.

2021-12-153 citations

10.1007/s12471-021-01649-5

Usefulness of oral anticoagulation in patients with coronary aneurysms: Insights from the CAAR registry

Fabrizio D’Ascenzo, Andrea Saglietto, Harish Ramakrishna, Alessandro Andreis, Jesús Jiménez‐Mazuecos et al. (14 authors)

Catheterization and Cardiovascular Interventions2020-09-0917 citations

10.1002/ccd.29243

P871Coronary artery aneurysms: clinical features, management and long-term outcomes, insights from the international coronary artery aneurysm registry (CAAR)

Iván J. Núñez‐Gil, Enrico Cerrato, Mario Bollati, Luis Nombela‐Franco, Emilio Alfonso et al. (15 authors)

European Heart Journal2019-10-01

10.1093/eurheartj/ehz747.0468

Rationale and design of a multicenter, international and collaborative Coronary Artery Aneurysm Registry (<scp>CAAR</scp>)

Iván J. Núñez‐Gil, Luis Nombela‐Franco, Rodrigo Bagur, Mario Bollati, Enrico Cerrato et al. (32 authors)

Clinical Cardiology2017-03-2420 citations

10.1002/clc.22705

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

No

Inclusion criteria

(angiographic diagnosis): * Coronary aneurysm: focal coronary dilatation which exceeds the diameter of normal adjacent segments or the diameter of the patient's largest coronary vessel by 1.5 times.

Exclusion criteria

* Patient ´s refusal to participate.

Design outcomes

Primary

Measure	Time frame	Description
Any cause death	12 months	dicotomic variable (yes/no)
Cardiology readmission	12 months	dicotomic variable (yes/no)

Countries

Spain

Outcome results