Airway Resistance Measurement in Children 3 to 6 Years of Age

Interrupter Technique and Plethysmography Airway Resistance Measurement: Comparison of These Two Techniques for the Diagnosis of Airway Obstruction Diagnosis and Bronchodilation Response in Children 3 to 6 Years of Age

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02563210

Acronym

ARC36

Enrollment

130

Registered

2015-09-30

Start date

2015-10-19

Completion date

2017-05-29

Last updated

2019-04-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Airway Obstruction

Brief summary

In preschool aged children, the most suitable techniques to assess airway obstruction is debit interruption technic (Rint) and plethysmographic measure of specific airway resistance (sRaw). Even if Rint is easily and routinely performed, it also includes a component of lung tissue and chest wall resistance as well as respiratory tissue viscoelasticity. sRaw seems to be better for discriminating airway obstruction. These two techniques will be compared in terms of concordance in the diagnosis of pulmonary obstruction and bronchodilator response.

Interventions

OTHERairway resistance measurement

assessment of airway resistance

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

DIAGNOSTIC

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

3 Years to 6 Years

Healthy volunteers

Inclusion criteria

* Child 3 to 6 years aged

Exclusion criteria

* Height below 90 centimeters * Opposition to participation

Design outcomes

Primary

Measure	Time frame	Description
airway resistance measure by interruption technique (Rint)	Day one	Rint is performed using Spiroteq Dyn'R during a 100 ms occlusion and calculated using the linear back extrapolation method

Secondary

Measure	Time frame	Description
measure of bronchodilator response	Day one	Bronchodilator response is assessed with Rint and sRaw measurement

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026