Effect of Left Atrial Appendage Excision on Procedure Outcome in Patients With Persistent and Long-standing Persistent Atrial Fibrillation Undergoing Surgical Ablation

Status

UNKNOWN

Phases

Phase 2

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02562391

Enrollment

180

Registered

2015-09-29

Start date

2011-05-31

Completion date

2017-05-31

Last updated

2015-09-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atrial Fibrillation

Keywords

atrial fibrillation, ablation, thoracoscopy, left atrial appendage

Brief summary

The aim of this study is to assess the effect of left atrial appendage excision on atrial fibrillation recurrence and incidence of stroke in patients with persistent and long-standing persistent atrial fibrillation undergoing surgical ablation.

Interventions

DEVICESurgical ablation of the left atrium (PVI+Box lesions)

DEVICESurgical ablation of the left atrium (PVI+Box lesions) and left atrial appendage cutting

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 80 Years

Healthy volunteers

Inclusion criteria

Key Inclusion Criteria: * Patients with persistent and long-standing persistent atrial fibrillation eligible for thoracoscopy surgical ablation * Signed inform consent Key

Exclusion criteria

* Paroxysmal atrial fibrillation * Contraindications for surgical ablation * Unwilling to participate

Design outcomes

Primary

Measure	Time frame
Atrial fibrillation recurrences	18 months

Countries

Russia

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026