Immediate Hypersensitivity
Conditions
Brief summary
Skin prick test (SPT) was used for diagnostic test for type 1 hypersensitivity. The efficacy and safety of SPT were proved. The positive control of SPT is histamine. In Thailand, the most common concentration of histamine for SPT is 10 mg/ml. However, in some practice they use other concentration (1, 2.5 mg/ml). This study will find the proper concentration of histamine for positive control use in SPT.
Detailed description
Appropriate concentration of histamine positive control is important in interpretation the result of skin prick test.
Interventions
PROCEDURESPT
SPT of histamine concentration 1, 5 and 10 mg/ml
Sponsors
Mahidol University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
7 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
* Parcitipate person who attented allergy clinic, ENT clinic * Legible in Thai language
Exclusion criteria
* Patient cannot withhold antihistamine drug * Pragnancy and lactation mother * comorbid disease such as cardiac disease, liver, renal, hypertension and severe asthma
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Mean wheal diameters of SPT of different histamine concentrations. | 1 years | compare mean wheal diameters of histamine concentration 1,5, and 10 mg/ml |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Mean wheal diameters of SPT of local and imported histamine positive concentration | 1 year | compare mean wheal diameters of imported histamine 1 mg/ml to local histamine |
Countries
Thailand
Outcome results
None listed