Cardiomyopathy
Conditions
Brief summary
This study will evaluate the prognostic utility of novel ECG markers of electrical instability in patients with cardiomyopathy.
Detailed description
Baseline ECG markers of electrical instability will be measured in patients with cardiomyopathy. These ECG markers will be evaluated from a clinical Holter recording. All patients will have a primary implantable cardioverter defibrillator (ICD) as part of their clinical care. Patients will be followed prospectively for 2 years to evaluate the primary outcome of appropriate ICD shocks. Multivariable modelling will be performed to determine whether the ECG markers of electrical instability independently predict the primary clinical outcome.
Interventions
None listed
Sponsors
University Health Network, Toronto
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* cardiomyopathy, primary prevention ICD
Exclusion criteria
* brady-pacing requirement
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Proportion of patients with appropriate implantable cardioverter defibrillator (ICD) shocks | 2 years | Proportion is from 0 (no patients with shocks) to 100% (all patients receive shocks) |
Countries
Canada
Outcome results
None listed