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Effects of Pomegranate Juice on Oxidative Stress in Patients With type2 Diabetes

Effects of Pomegranate Juice Consumption on Glycemic Control, Lipid Profile, Oxidative Stress and Blood Pressure in Patients With Type 2 Diabetes

Status
Completed
Phases
Phase 4
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02559843
Enrollment
60
Registered
2015-09-24
Start date
2014-11-30
Completion date
2015-02-28
Last updated
2015-09-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetes Type 2

Keywords

pomegranate, diabetes, oxidative stress

Brief summary

Introduction: Diabetes mellitus a chronic diseases, is the most common and important metabolic disease in human. Increased free radicals production due to hyperglycemia produces oxidative stress which worsens the disease and its complications. Pomegranate juice has antioxidant and antiatherosclerotic properties. The present study was planned to evaluate the effects of pomegranate juice consumption on glycemic control, lipid profile,blood pressure and oxidative stress in patients with type 2 diabetes

Interventions

DIETARY_SUPPLEMENTpomegranate juice
BEHAVIORALlifestyle modification

Sponsors

National Nutrition and Food Technology Institute
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
40 Years to 65 Years
Healthy volunteers
No

Inclusion criteria

* Age of 40-65 years * Body Mass Index 18.5-30 * Fasting blood glucose ≥ 126 mg/dl

Exclusion criteria

* Smoking * insulin for blood glucose control * taking estrogen or progesterone (if female) * Taking antioxidant supplements * suffering from any other chronic diseases * Participants are also excluded if they missed more than 10% of their pomegranate juice packs

Design outcomes

Primary

MeasureTime frame
total antioxidant capacity6 weeks

Secondary

MeasureTime frame
fasting blood glucose6 weeks

Countries

Iran

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026