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Transcriptomics Signature of Anti Vaccinia Memory B Cells

Transcriptomics Signature of Anti Vaccinia Memory B Cells in Healthy Individuals at a Short Time After Vaccination

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT02556489
Enrollment
4
Registered
2015-09-22
Start date
2015-11-03
Completion date
2018-02-05
Last updated
2026-06-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy

Keywords

immunological memory

Brief summary

Analyse the transcriptomic signature of anti vaccinia memory B cells at a short time after vaccination as compared to the signature already established in long-lived memory B cells.

Interventions

None listed

Sponsors

Institut National de la Santé Et de la Recherche Médicale, France
Lead SponsorOTHER_GOV

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
20 Years to 50 Years
Healthy volunteers
Yes

Inclusion criteria

* Healthy donors vaccinated against smallpox

Exclusion criteria

* none

Design outcomes

Primary

MeasureTime frameDescription
Analysis of B memory cells12 monthsB-memory cells will be analysed to determine, on an individual basis, whether they express the long-lived signature

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jun 9, 2026