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Cost Effectiveness Analysis of Critical Care in Resource Limited Setting

Cost Effectiveness of Intensive Care in a Low Resource Setting: Prospective Cohort of Medical Critically Ill Patients

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT02556476
Acronym
CEACCLR
Enrollment
148
Registered
2015-09-22
Start date
2011-06-30
Completion date
2013-06-30
Last updated
2015-09-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Critical Illness

Keywords

critical care, intensive care, health related quality of life, cost benefit analysis

Brief summary

The purpose of this study was to examine the cost effectiveness of critical care in a middle income country with limited resources. The main study hypothesis was that critical care is cost effective in low resources setting.

Detailed description

The investigators objective was to calculate the cost effectiveness of treatment of critically ill patients in a medical ICU of a middle income country with limited access to ICU resources. Methods: Consecutive critically ill medical patients treated in a recently established medical ICU in Sarajevo, Bosnia and Herzegovina, were prospectively recorded and a subsequent cost utility analysis of intensive care in comparison to hospital ward treatment from the perspective of health care system was performed. Incremental cost effectiveness was calculated using estimates of ICU versus non-ICU treatment effectiveness based on a formal systematic review of published studies. Decision analytic modeling was used to compare treatment alternatives. Sensitivity analyses of the key model parameters were performed.

Interventions

PROCEDUREmechanical ventilation

ventilator support for the patients presenting with acute respiratory failure

PROCEDUREneuromuscular blockade

paralysis of the skeletal muscles in order to optimize mechanical ventilation, especially during ARDS

PROCEDURErenal replacement therapy

the procedures used to treat acute kidney injury

PROCEDUREnon-invasive ventilation

Procedure used for ventilation support in patients with congestive heart failure, pulmonary edema, COPD and some other conditions.

Sponsors

University of Sarajevo
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

* patients treated between June 1 2011 and June 29 2012 in the medical ICU

Exclusion criteria

* Patients who stayed in the ICU less than 24 hours and * hospital readmissions

Design outcomes

Primary

MeasureTime frameDescription
survivalone year after hospital releasemortality was recorded one year after hospital discharge and subtracted from the value od 100% in order to get one year survival

Secondary

MeasureTime frameDescription
mortality30 days and 60 days after critical illness onset and one year after hospital release
health related quality of life (HRQOL)one year after hospital releaseHRQOL was assessed using EQ5D-3L questionnaire

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026