Skip to content

Location of Injection of Local Anesthetics in the Adductor Canal Block

Location of Injection of Local Anesthetics in the Adductor Canal Block: A Randomized Controlled Trial of the Effect on Postoperative Analgesia and Motor Power

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02554864
Acronym
LILAC
Enrollment
108
Registered
2015-09-18
Start date
2016-02-22
Completion date
2018-01-02
Last updated
2019-02-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Adductor Canal Block, Anesthesia

Brief summary

The adductor canal block (ACB) is the standard of care for analgesia after Anterior Cruciate Ligament (ACL) repair. ACB is performed by injecting local anesthetic (freezing) in the subsartorial canal in the thigh which is about 7-10cm long. Preliminary evidence suggests that different injection sites within the canal may produce different degrees of analgesia and quadriceps motor block. This trial seeks to determine the effects of various ACB injection sites on postoperative analgesia and motor power following ACL repair.

Detailed description

Adductor canal block (ACB) is replacing femoral nerve block (FNB) as the peripheral nerve block of choice for knee surgery. The ACB aims to inject local anesthetics (LA) within the neurovascular sheath in the subsartorial adductor canal around the femoral nerve. The point where the sartorius muscle crosses over the femoral artery is generally the accepted site for performing ACB. Clinically, injecting LA in the adductor canal blocks the sensory innervation of the knee and thus offers pain relief that is similar to FNB while conserving motor power around the knee. While these benefits are desirable, the exact location for performing ACB that ensures these benefits, remains debatable. The subsartorial adductor canal itself is 7-10cm long and the anatomical location of the sensory and motor nerves that innervate the knee and its surrounding muscles in this canal may vary. This randomized controlled trial is designed to identify and refine the ACB technique by clinically determining the effects of various ACB injection locations on postoperative analgesia and quadriceps motor power following ACL repair.

Interventions

DRUGlidocaine

Local anesthetic

DRUGropivacaine

Local anesthetic

Sponsors

Women's College Hospital
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Caregiver, Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
18 Years to 50 Years
Healthy volunteers
No

Inclusion criteria

* Patients booked for anterior cruciate ligament surgery under general anesthesia * English speaking * BMI \<38 kg/m2

Exclusion criteria

* Refusal or inability to provide informed consent * Allergy to local anesthetics * Contraindication to regional anesthesia including coagulopathy or bleeding - diathesis * Infection * Nerve Injury at the site of the nerve block * Malignancy at the site of the nerve block * History of drug and/or alcohol dependence * History of long term opioid intake or chronic pain disorder * History of pre-existing neuropathy in the operative leg * History of significant psychiatric conditions that may affect patient assessment * Inability to understand the informed consent and demands of the study * Allergy to any of the components of multi-modal analgesic regimen * Revision ACL repair

Design outcomes

Primary

MeasureTime frameDescription
Cumulative 24 Hour Oral Morphine Equivalent Consumption24 hoursPost-Operative Analgesia
Motor Power - Peak Force as measured by a dynamometer30 Minutes post BlockPercentage decrease in quadriceps motor strength at 30 minutes following adductor canal block compare to baseline

Secondary

MeasureTime frameDescription
Pain Scores - Questionnaire24 hours post blockArea under the curve for rest pain scores plotted against time during the first 24 hours
Quality of Recovery (QoR-15)24 hours postoperativelyQuality of recovery measured using the QoR-15 at 24 hours postoperatively
Opioid ConsumptionDuring surgical procedureIntra-operative opioid consumption
Hospital Discharge (Time to hospital discharge)Same day as surgical procedureTime to hospital discharge
Nerve Block Complications24 hours postoperatively and 2 weeks postoperativelyPresence/absence of nerve block complications during the first 24 hours postoperatively and 2 weeks after surgery
Patient Satisfaction - Questionnaire24 hours postoperativelyPatient satisfaction with analgesia - NRS Pain Scale 0(no pain to 10(worst pain)
Total opioids in Post Anesthetics (PAC)Total length of time in PACU (total time in minutes from arrival in PACU to discharge to the Surgical Day Care is between 60-180 minutesCumulative oral morphine equivalent consumption in PACU

Countries

Canada

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026