Measurements of Exhaled Nitric Oxide in Healthy Subjects in Thailand

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02554617

Acronym

FeNO_nor

Enrollment

100

Registered

2015-09-18

Start date

2010-10-31

Completion date

2015-08-31

Last updated

2016-05-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Normal Non-fluency

Keywords

healthy people, fractional exhaled nitric oxide (FeNo), factors

Brief summary

The purpose of this study is to determine fractional exhaled nitric oxide (FeNO) level in healthy subjects among Thai populations.

Detailed description

Fractional exhaled nitric oxide (FeNO) were produced from epithelial cells of inflammatory airways and eosinophils and this gas was discovered since 1991. Fractional exhaled nitric oxide (FeNO) has direct association with severity of inflammation of bronchial trees and sputum eosinophils and use for additional investigation for diagnosis asthma or inflammatory airway diseases. There are many factors from previous studies that associate with level of fractional exhaled nitric oxide (FeNO), one of that factors is race therefore we can't use level from another studies with different race for use as reference and there is no study about level of fractional exhaled nitric oxide in Thai population. It is therefore desirable to examine level of fractional exhaled nitric oxide (FeNO) in healthy subjects among Thai population and will be the main objective of this research.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

6 Years to 60 Years

Healthy volunteers

Yes

Inclusion criteria

* healthy subjects in community

Exclusion criteria

* smoker or past history of smoking * asthma, allergic rhinitis, chronic respiratory disease or other chronic illness * history of wheezing within 12 months before enrollment * history of upper or lower respiratory tract infection within 6 weeks before enrollment * drink ethanol within 48 hours before enrollment * drink caffeine within day before enrollment * during pregnancy * chronic use of any drugs * participate other project within 30 days

Design outcomes

Primary

Measure	Time frame
fractional exhaled nitric oxide level	10 minutes (average time ), on the day of enrollment

Countries

Thailand

Outcome results