Reduction of Postoperative Pain After Milligan-Morgan Haemorrhoidectomy With Application of Vitamin E Ointment

Reduction of Postoperative Pain and Improvement of Patients´Comfort After Milligan-Morgan Haemorrhoidectomy With Application of Vitamin E Ointment

Status

Completed

Phases

Phase 3

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02554123

Enrollment

Registered

2015-09-18

Start date

2015-01-31

Completion date

2015-09-30

Last updated

2015-09-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain

Brief summary

A prospective ranfomized clinical study of patients undergoing Milligan Morgan´s haemorrhoidectomy at Hospital Universitario Rey Juan Carlos (Móstoles-Spain) will be performed. The patients will be randomized into 2 groups: * Experimental group (EG): Patients undergoing Milligan Morgan´s procedure and application of Vitamin E ointment on the surgical bed. * Control group (CG): Patients undergoing Milligan Morgan´s procedure and application of Vaseline on the surgical bed. Postoperative pain determined by VAS at the 1st, 3rd and 7th postoperative days, and need for morphine rescue will be investigated.

Detailed description

Interventions

DRUGVitamin E ointment application

Vitamin E ointment application. Every 12 hours during 7 days.

DRUGVaseline ointment application

Vaseline ointment application. Every 12 hours during 7 days.

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* Patients undergoing Milligan Morgan´s haemorrhoidectomy at Hospital Universitario Rey Juan Carlos (Móstoles-Spain). * Haemorrhoids grade III and IV * The patients sign an Informed Consent Form agreeing their participation in the study.

Exclusion criteria

* Patients undergoing other surgical techniques for haemorrhoidectomy, different tan Milligan Morgan * Haemorrhoids grade I and II * Patients with medical or surgical pathologies that do not allow the participation in the study * Disability to understand and accept the entry in the study

Design outcomes

Primary

Measure	Time frame	Description
Postoperative pain	From the first to the 7th postoperative days	Postoperative pain will be quantified with a VAS scale at the 1st, 3rd and 7th postoperative days

Secondary

Measure	Time frame	Description
Need for morphine rescue	24 hours after surgery	Need for morphine rescue will be quantified in the first 24 hours after surgery during the hospital stay

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026