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Subfoveal Choroidal Thickness in Thai Population

Subfoveal Choroidal Thickness in Thai Population

Status
Terminated
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT02551601
Enrollment
150
Registered
2015-09-16
Start date
2015-08-31
Completion date
2018-08-31
Last updated
2019-08-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy

Keywords

subfoveal choroidal thickness, optical coherence tomography, enhanced depth imaging

Brief summary

The purpose of this study was to determine the subfoveal choroidal thickness in normal Thai eyes and study the associations with gender, age, refractive error and axial length using spectral-domain optical coherence tomography with enhanced depth imaging technique.

Detailed description

Alteration of choroidal blood supply causes changes in choroidal thickness and results in choroidal abnormalities. These are usually associated with retinal diseases and leading to severe visual dysfunction. Choroidal thickness is therefore helpful in diagnosis and treatment for many chorioretinal conditions. With the advent of spectral domain optical coherence tomography and enhanced depth imaging technique, choroidal thickness has been investigated widely in normal eyes and various chorioretinal diseases including central serous chorioretinopathy (CSC), age-related macular degeneration (AMD), highly myopia and Vogt Koyanagi-Harada disease. Similar to retinal thickness, a normal baseline choroidal thickness might be used for interpretation. This value might be affected by several variables including age, gender and ethnicity. Although there were previous studies on subfoveal choroidal thickness in normal eyes from many countries, there has been no such study in Thailand. The purpose of this study was to determine the subfoveal choroidal thickness in normal Thai eyes and study the associations with gender, age, refractive error and axial length using SD-OCT and EDI technique.

Interventions

OTHERmeasure subfoveal choroidal thickness

measure subfoveal choroidal thickness using optical coherence tomography

Sponsors

Khon Kaen University
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* Age 18 years or above * Healthy subjects * No ocular diseases * Written informed consent form

Exclusion criteria

* patients with systemic diseases that may affect retinal or choroidal thickness including diabetes * patients with history of refractive surgeries, intraocular surgeries or retinal laser treatments * patients with history of macular, retinal, or optic nerve abnormalities

Design outcomes

Primary

MeasureTime frameDescription
subfoveal choroidal thicknessup to 4 monthsThickness of choroid at the foveal area

Countries

Thailand

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026