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Prognostic Value of Residual Hypoventilation in Mechanically Ventilated Neuromuscular Patients

Prognostic Value of Residual Hypoventilation in Mechanically Ventilated Neuromuscular Patients

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT02551406
Acronym
TcCO2-VAD
Enrollment
55
Registered
2015-09-16
Start date
2015-09-30
Completion date
2015-12-31
Last updated
2016-02-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Home Mechanical Ventilation, Neuromuscular Disease

Keywords

nocturnal hypoventilation, capno-oxymetry

Brief summary

Different tools may be used to monitor the efficacy of home mechanical ventilation. Investigators aimed to compare the prognostic value of the different data obtained by capno-oxymetry in a mechanical ventilated neuromuscular disease's population.

Detailed description

Home mechanical ventilation (HMV) is used to treat hypoventilation, and its efficacy is mostly assessed by daytime blood gases and nocturnal oxymetry (SpO2). Transcutaneous CO2 measure (TcCO2) has shown higher sensitivity than SpO2 to detect hypoventilation in neuromuscular diseases (NMD) patients. No data exist on the prognostic value of these techniques to monitor mechanical ventilated NMD patients. Basing on retrospective data review, investigators aimed to compare the prognostic value of the data obtained using different tools to assess residual hypoventilation in the cohort of ventilated NMD patients followed at our reference center.

Interventions

DEVICECapno-oxymetry monitoring

Monitoring of home mechanical ventilation by capno-oximetry

Sponsors

Centre d'Investigation Clinique et Technologique 805
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* neuromuscular disease * age ≥18 years * mechanically ventilated * capno-oxymetry performed between 2009 and 2011

Exclusion criteria

* Long-term oxygen therapy

Design outcomes

Primary

MeasureTime frameDescription
Time to first ICU admission6 yearsTime to first ICU admission

Secondary

MeasureTime frameDescription
Mortality6 yearsTime to death

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 1, 2026