Hepatocellular Carcinoma
Conditions
Keywords
MR/PET, hepatocellular carcinoma, HCC
Brief summary
The purpose of this study is to explore the ability of integrated MRI/PET to detect and evaluate treatment outcome in HCC patients.
Detailed description
This study using 18F-FDG PET and functional MRI (DCE-MRI, Diffusion-weighted MRI, MR spectroscopy).
Interventions
The purpose of this study is to explore the ability of integrated MRI/PET to detect and evaluate treatment outcome in HCC patients. This study using 18F-FDG PET and functional MRI (DCE-MRI, Diffusion-weighted MRI, MR spectroscopy).
Sponsors
National Taiwan University Hospital
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
20 Years to 90 Years
Healthy volunteers
No
Inclusion criteria
1. Prior Informed Consent Form 2. At least one measurable tumor, according to RECIST version 1.1. 3. Age \> 20 years. 4. ECOG performance status 0 or 1. 5. Life expectancy \> 3 months. 6. Confirmed Diagnosis of HCC 7. Adequate renal function (Serum creatinine ≦ 1.5 x upper limit of normal).
Exclusion criteria
1. Age \<20 years old 2. Pregnancy 3. Contraindication for MRI: claustrophobia or MR non-compatible devices 4. Contraindication for MR contrast medium: severe adverse reaction or impaired renal function (Cre \> 2.0) 5. History of other malignancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The recurrence rate at 3 months after treatment | 3 months |
Secondary
| Measure | Time frame |
|---|---|
| The overall survival after treatment | 1 year |
Countries
Taiwan
Contacts
Primary ContactTing-Fang Shih, MD
Outcome results
None listed