Wound Closure Techniques
Conditions
Brief summary
The purpose of this study is to determine whether the use of 2-octylcyanoacrylate during repair of cutaneous surgery wounds with full-thickness skin grafts improves scar cosmesis compared to wound closure with sutures.
Detailed description
The purpose of this study is to determine whether the use of 2-octylcyanoacrylate during repair of cutaneous surgery wounds with full-thickness skin grafts improves scar cosmesis compared to wound closure with sutures. Our aims are to compare outcomes using a split wound model, where half of the wound is treated with 2-octylcyanoacrylate and the other half is repaired with sutures, per the standard of care. Three-months post-surgery, the scar will be measured via the physician observer scar assessment scale, a validated scar instrument. Our hypothesis is that 2-octylcyanoacrylate will result in cosmetically superior wound outcomes.
Interventions
PROCEDUREWound Closure with 5-0 Vicryl Sutures
Sponsors
University of California, Davis
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Over 18 years of age * Able to give informed consent themselves * Patient scheduled for cutaneous surgical procedure with predicted closure with full-thickness skin graft * Willing to return for follow-up visits
Exclusion criteria
* Mentally handicapped * Unable to understand written and oral English * Incarceration * Under 18 years of age * Pregnant Women * Patients on systemic steroid therapies * Patients with Marfans * Patients with allergies to 2-octylcyanoacrylate
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Appearance of Scar on the Patient and Observer Scar Assessment Scale | 3 months | After surgical procedure, half of the subject's wound will be with 2-octylcyanoacrylate, while the other half is closed 5-0 vicryl sutures. After 3 months, subjects will return to clinic for evaluation of the cosmesis of both types of closure techniques. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Incidence of Graft Failure on Case Report | 3 months | The secondary endpoint will include incidence of graft failure (partial and complete on both sides). |
| Incidence of Complications on Case Report | 3 months | Noting the presence or absence of bleeding, dehiscence, infection or spitting sutures. |
Outcome results
None listed