Analgesia, Obstetrical
Conditions
Brief summary
The aim of this study is to assess whether tenoxicam is as effective as pethidine for analgesia during the first stage of labor.
Interventions
DRUGTenoxicam
DRUGPethidine
Sponsors
Ain Shams Maternity Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
FEMALE
Age
20 Years to 30 Years
Healthy volunteers
Yes
Inclusion criteria
* Primiparity * Active phase of labor (cervical dilatation of 3-5 cm, in the presence of adequate uterine contractions; lasting at least 40 seconds at intervals of 3-4 minutes) * Maternal age between 20-30 years * Singleton term pregnancy (37-42 weeks of gestation) * Vertex-presenting fetus
Exclusion criteria
* Clinical evidence of cephalopelvic disproportion * Scarred uterus; previous cesarean section, hysterotomy or myomectomy * Medical disorders associated with pregnancy, especially gastritis, peptic ulcer, bronchial asthma or renal impairment * Fetal distress * Receiving any regional or parenteral analgesia before recruitment in the study * Known hypersensitivity to the drug family
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The efficacy of intravenous tenoxicam to supply adequate analgesia as indicated by changes in the pain intensity score using the visual analog scale | 4 hours | Assessment is to be done and followed up by the investigator at ½, 1, 2, 3 and 4 hours from drug administration. Scores range from 0 \[no pain\] to 10 \[worst possible pain\]. |
Outcome results
None listed