Kidney Failure
Conditions
Keywords
haemodialysis, hypotension
Brief summary
This is a prospective observational pilot study of patients under the care of the Royal Free Hospital with chronic kidney disease who have been established on regular thrice weekly haemodialysis treatments in a dialysis centre,to measure the changes in blood flow in the ear during haemodialysis.
Detailed description
10 patients, attending for thrice weekly outpatient haemodiafiltration shall be studied during a dialysis session using a CE marked commercially available digital otoscope capable of recording digital videos of the tympanic membrane and ear canal. Patients will receive standard clinical care and monitoring of their dialysis session, which includes recording of blood pressure and changes in haematocrit and volume status during dialysis and noting patient symptoms.
Interventions
OTHERno intervention
observational study
Sponsors
University College, London
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* Patients age 18 years and older up to 80 years * Under the care of the Royal Free Hospital with chronic kidney disease and established on regular thrice weekly haemodiafiltration. * Able to provide written informed consent obtained
Exclusion criteria
* Patients unable to provide written informed consent * Patients using hearing aids * Patients who have had previous middle ear surgery * Patients not fulfilling inclusion criteria
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| change in ear blood flow | day 1 dialysis session | percentage change in ear blood flow compared to initial ear blood flow |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| change in blood pressure | day 1 dialysis session | change in blood pressure in mmHg compared to starting blood pressure |
| change in haematocrit volume status | day 1 dialysis session | percentage change in haematocrit |
| record of hypotensive episodes during dialysis | day 1 dialysis session | record of nursing interventions including reduction in ultrafiltration volume, administration of intravenous fluids. Use of distress thermometer visual analogue scale to record patient symptoms |
Countries
United Kingdom
Contacts
Primary Contactvashist deelchand
Outcome results
None listed