Enlarged Pores
Conditions
Keywords
Enlarged pores, Er:YAG laser
Brief summary
To investigate the efficacy of Erbium:Yttrium aluminum garnet laser (Er:YAG) in the treatment of enlarged pores.
Detailed description
* Enlarged pores are caused by multifactorial factors such as sex, genetics, aging, etc. * The gold of the treatment is to recollagenesis of the dermis and resurfacing of the epidermis. * Modalities that have been proved on their efficacy for enlarged pores treatment included topical retinoic acid, chemical peeling, intense pulsed light, radiofrequency device, laser such as Q-switched and Long Pulsed Neodymium-Doped Yttrium-Aluminum-Garnet (Nd:YAG) 1,064nm, Long pulse duration pulsed dye laser 595nm, etc. * Er:YAG laser is an ablative laser which creates both recollagenesis and resurfacing. It ha been proved to be safe and effective in the treatment of atrophic acne scar. * However, the efficacy of this laser for enlarged treatment has not yet been established.
Interventions
DEVICEEr:YAG laser
Er:YAG laser treats enlarged pores on both sides of the face for 4 treatments of 1 month interval.
Sponsors
Mahidol University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
25 Years to 60 Years
Healthy volunteers
Yes
Inclusion criteria
* Visible enlarged pores on both sides of the face * Fitzpatrick skin type 3-5
Exclusion criteria
* Patients with lesions with any clinical suspicion of being pre-cancerous or skin malignancies of any kind * Patients who have photosensitive dermatoses * Pregnancy and lactation woman * Patients with wound infections (herpes, other) on the day of treatment * Patients with moderate and severe inflammatory acne, Immunosuppressed patients, history of vitiligo * Patients with unrealistic concerns/expectations and inability to do the appropriate post-operative care
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The efficacy of Er:YAG laser in the treatment of enlarged pores (measurement of skin texture using UVA-light video camera) | 1 month after 4 treatments | measurement of skin texture using UVA-light video camera |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Hyperpigmentation side effect of Er:YAG laser in the treatment of enlarged pores | Follow-up period:1 month after 1st treatment, 1 month after 2nd treatment, 1 month after 3rd treatment and 1-,3-,and 6-month after 4th treatment | By investigators' observation of hyperpigmentation |
| Hypopigmentation side effect of Er:YAG laser in the treatment of enlarged pores | Follow-up period:1 month after 1st treatment, 1 month after 2nd treatment, 1 month after 3rd treatment and 1-,3-,and 6-month after 4th treatment | By investigators' observation of hypopigmentation |
| Erythema side effect of Er:YAG laser in the treatment of enlarged pores | Follow-up period:1 month after 1st treatment, 1 month after 2nd treatment, 1 month after 3rd treatment and 1-,3-,and 6-month after 4th treatment | By investigators' observation of erythema |
| The patients satisfaction using Quartile grading scale of improvement | Follow-up period:1 month after 1st treatment, 1 month after 2nd treatment, 1 month after 3rd treatment and 1-,3-,and 6-month after 4th treatment | By using Quartile grading scale of improvement; 0 = not improve, 1= 1-25% improvement, 2 = 26-50% improvement, 3 = 51-75% improvement and 4 = 76-100% improvement |
Countries
Thailand
Outcome results
None listed