Postoperative Analgesic Effects of Using Dexmedetomidine for Ultrasound Guided Thoracic Paravertebral Block

Postoperative Analgesic Effects of Using Bupivacaine Alone or Added Dexmedetomidine for Ultrasound Guided Thoracic Paravertebral Block in Thoracotomy

Status

Completed

Phases

Phase 4

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02544893

Enrollment

Registered

2015-09-09

Start date

2015-09-30

Completion date

2016-03-31

Last updated

2016-08-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain

Brief summary

we aimed postoperative analgesic effects of using bupivacaine alone or added dexmedetomidine for ultrasound guided thoracic paravertebral block in thoracotomy

Detailed description

paravertebral block is commonly used in the treatment for acute and chronic pain.The duration of paravertebral block could theoretically be prolonged with neurolytic agents. Dexmedetomidine ,an alfa-2 adrenoreceptor agonist, is being used and adjuvant capable of prolonging duration of sensory and motor block on nerve blocks.

Interventions

DRUGbupivacaine

21 ml 0.5 %bupivacaine is applied paravertebral space

DRUGdexmedetomidin

1 ml dexmedetomidin + 20 ml 0.5 % bupivacaine are applied paravertebral space

DRUGserum physiologic

21 ml serum physiologic is applied paravertebral space

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

TREATMENT

Masking

QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Inclusion criteria

* ASA 1-2 * 18-65 aged * patient undergoing thoracotomy

Exclusion criteria

* chronic opioid consumption * bupivacaine and dexmedetomidine allergies * coagulopathy * infection at the needle insertion side * chronic liver and kidney disease

Design outcomes

Primary

Measure	Time frame	Description
opioid consumption	postoperative 24 hours	patient controlled analgesia

Secondary

Measure	Time frame	Description
visual analog scale	postoperative 1 day	visual analog scale

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026