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Are Doctors Familiar With the Test Characteristics of Lung Cancer Screening?

Are Doctors Familiar With the Test Characteristics of Lung Cancer Screening?

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02542332
Enrollment
556
Registered
2015-09-07
Start date
2015-05-31
Completion date
2015-08-31
Last updated
2015-09-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Information About the Knowledge on the Statistical Background of Lung Cancer Screening of Doctors

Keywords

lung cancer screening, statistical background

Brief summary

This study evaluates whether doctors are familiar with the statistical background of lung cancer screening.

Detailed description

Background: Screening with low-dose CT scan can prevent three deaths due to lung cancer among 1000 high-risk individuals. However, false-positive results and radiation exposure are relevant disadvantages deserving accurate consideration. Candidates for screening can only make an autonomous decision if doctors inform them correctly about the pros and cons of the method. Therefore, this study aims to evaluate, whether doctors understand the test characteristics of lung cancer screening. Methods: In a randomized trial, 556 doctors (members of the Austrian Respiratory Society) will be invited to answer questions regarding lung cancer screening based on online case vignettes. Half of the participants will be randomized to the group 'with data' and will receive the correct solutions in advance. The group 'without data' will have to rely on prior knowledge or estimate. Primary endpoint will be the between-groups difference in the estimated number of deaths preventable by screening. Secondary endpoints will be the between-groups differences in prevalence of lung cancer, prevalence of suspicious results, sensitivity, specificity, positive-predictive value, and false negative rate. Estimations will also be compared to actual values from the literature.

Interventions

OTHERWith Data

The participants received statistical data about lung cancer screening in order to help them answer the questionaire

Sponsors

Otto Wagner Hospital
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
HEALTH_SERVICES_RESEARCH
Masking
NONE

Eligibility

Sex/Gender
ALL
Healthy volunteers
Yes

Inclusion criteria

* Doctors, who were in training or had a completed specialization training in: * Pneumonology * Internal Medicine * Surgery * or Radiology

Exclusion criteria

* Doctors, with a specialized training in * ENT * Pediatrics * Pathology and doctors who had no e-mail address were excluded.

Design outcomes

Primary

MeasureTime frameDescription
Between-groups difference in the estimated reduction of mortality due to lung cancer screening14 daysParticipants had 14 days to complete the survey

Secondary

MeasureTime frameDescription
Between-groups difference prevalence of lung cancer14 daysParticipants had 14 days to complete the survey
Between-groups difference in sensitivity of lung cancer screening14 daysParticipants had 14 days to complete the survey
Between-groups difference in the frequency of a positive test result14 daysParticipants had 14 days to complete the survey
Between-groups difference in positive predictive value of lung cancer screening14 daysParticipants had 14 days to complete the survey
Between-groups difference in the false negative rate of lung cancer screening14 daysParticipants had 14 days to complete the survey
Between-groups difference in specificity of lung cancer screening14 daysParticipants had 14 days to complete the survey

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Mar 7, 2026