Coagulation Disorders After Aneurysmatic Subarachnoid Haemorrhage

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02540005

Enrollment

Registered

2015-09-03

Start date

2015-09-30

Completion date

Unknown

Last updated

2016-06-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Aneurysmatic Subarachnoid Haemorrhage

Brief summary

The main purpose of this study is to analyse the on-going coagulation process after aSAH. For investigation the investigators use the rotational thromboelastometry (ROTEM) which is a point-of-care test using a variety of activators to provide a targeted and a dynamic analysis of coagulation cascade. This is a prospective, observational clinical study done in 16 aSAH patients treated in Tampere University Hospital intensive care unit and 16 control patients (elective craniotomy due to non-ruptured intracranial aneurysm.

Interventions

OTHERROTEM analysis

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Age ≥ 18 years * Acute subarachnoid haemorrhage (confirmed by computed tomography, CT, or cerebrospinal fluid erythrocyte count over 1000 x 106/l) AND confirmed origin either with computed angiography (CTA) or digital subtraction angiography (DSA) * Onset of symptoms ≤ 12 hours * Expected to stay 72 hours in the ICU

Exclusion criteria

* Pregnancy * Any long-term anticoagulant medication, except for low-dose aspirin (\<150 mg/day) * Known active cancer

Design outcomes

Primary

Measure	Time frame
ROTEM analysis: MCF (mm) by EXTEM activators	12 hours

Countries

Finland

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026