Skip to content

Impact of Smoking, Benzodiazepine (BZD) Use and Obesity on Severe Obstructive Sleep Apnea (sOSA)

Impact of Smoking, BZD and Obesity on Severe Obstructive Sleep Apnea (sOSA)

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT02539264
Enrollment
920
Registered
2015-09-03
Start date
2014-01-31
Completion date
2015-07-31
Last updated
2016-01-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity, Obstructive Sleep Apnea, Smoking

Keywords

All patients registered for A PSG, polysomnography

Brief summary

In this study the investigators will analyze the influence of smoking, benzodizepine use, and obesity among patients with severe Obstructive Sleep Apnea (sOSA).

Detailed description

This study is a retrospective study. Patients enrolled: all patients with a PSG (polysomnography) between 1st January 2014 and 30th June 2015. First analysis: influence of smoking, benzodiazepine use, and obesity on the AHI (Apnea Hypopnea Index: the number of apnea and hypopnea per hour of sleep). Second analysis: only among patients with sOSA: influence of smoking, benzodiazepine use, and obesity on sleep fragmentation and night oximetry.

Interventions

OTHERSmoking

Influence of smoking on parameters derived from overnight PSG

OTHERObesity

Influence of obesity on parameters derived from overnight PSG

OTHERBenzodiazepine use

Influence of benzodiazepine use on parameters derived from overnight PSG

Sponsors

Astes
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

* All patients registered for an overnight PSG at Clinique Saint-Luc of Bouge

Exclusion criteria

* None

Design outcomes

Primary

MeasureTime frameDescription
Apnea Hypopnea Index1 dayApnea Hypopnea Index (AHI) is defined as the number of apnea and hypopnea per hour of sleep. It is the major determinant of the severity of OSA.

Secondary

MeasureTime frameDescription
Sleep fragmentation defined by the percentage of time spent in each of the four stades of sleep (Stade 1, Stade 2, Slow wave sleep and Rapid Eye Movements)1 dayAre smoking and/or obesity a risk factor for sleep fragmentation?
Time spent under 90% of SpO2 during the night1 dayAre smoking and/or obesity a risk factor for oxygen desaturation (\< 90% SpO2) during the night?

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026