Depression
Conditions
Brief summary
This study evaluates the effect of metacognitive group therapy on depression compared to mindfulness groups and supportive groups. The participants, all with a history of depression and with current symptoms of depression, will be randomized to one of the three group interventions.
Detailed description
Metacognitive therapy (MCT) show promising results in alleviating depressive symptoms and reducing relapse of depression. However studies of MCT as a group intervention is limited and higher quality studies of the effectiveness of MCT is warranted. The present study aim to produce more conclusive evidence on the effect of MCT comparing MCT in groups with both and active control group and mindfulness based cognitive therapy (MBCT), which together with pharmacotherapy is currently one of the preferred treatment choices. Currently pharmacotherapy, cognitive therapy and MBCT seem to help 40-58% of the patients efficiently. The current studies of MCT indicate that this intervention may help a higher proportion of the patients.
Interventions
BEHAVIORALMetacognitive therapy
Group format, 10-12 participants in each group. 8 weekly sessions of two hours each.
BEHAVIORALMindfulness based cognitive therapy, group
Group format, 10-12 participants in each group. 8 weekly sessions of two hours each following the manual described by Williams, Zindel & Segal.
BEHAVIORALSupport groups
Group format, 10-12 participants in each group. The sessions will only be of supportive character and will not focus on changing or restructuring thoughts, scripts or thought patterns. The format will follow a manual but compared to the other intervention groups the format allow participants to suggests themes for discussions.
Sponsors
Center for Kognitive Terapier og Supervision
University of Southern Denmark
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* Consent to participate * History of clinical depression * Current depressive symptoms * Verbal and cognitive abilities to complete the questionnaires during the study * Stable medication - if any medication is ordinated * Speaks fluently danish
Exclusion criteria
* If criteria for psychosis, bipolar disorder or personality disorder is matched * known brain damage or mental retardation * substance abuse * women who are pregnant or breast feeding
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change from baseline on Hamilton depression scale | 8 weeks |
Secondary
| Measure | Time frame |
|---|---|
| Change from baseline on Becks depression inventory | 8 weeks |
| Change from baseline on Becks Anxiety Inventory | 8 weeks |
| Change from baseline on Ruminative Response Scale | 8 weeks |
| Change from baseline on Metacognitive questionnaire | 8 weeks |
Countries
Denmark
Contacts
Primary ContactMette E Andersen, PhD
Backup ContactTonny Andersen, PhD
Outcome results
None listed