Nocturnal Enuresis
Conditions
Keywords
Minirin, Oxybutynin, Nocturnal enuresis
Brief summary
Nocturnal enuresis is among the most common disorders in children. The aim of current study was to compare the efficacy and safety of Minirin and oxybutynin for treatment of nocturnal enuresis in children in Bandar Abbas in 2014.
Detailed description
Nocturnal enuresis is among the most common disorders in children. Several pharmacological and non-pharmacological treatments are available for nocturnal enuresis. Studies for reaching the best pharmacological treatment for this disorder are continuing. The aim of current study was to compare the efficacy and safety of Minirin and oxybutynin for treatment of nocturnal enuresis in children in Bandar Abbas in 2014.
Interventions
DRUGMinirin
Minirin 5 to 10 mg daily for 6 months
DRUGOxybutynin
Oxybutynin 5 to 10 mg daily for 6 months
Sponsors
Hormozgan University of Medical Sciences
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
5 Years to 14 Years
Healthy volunteers
No
Inclusion criteria
* \>5 years old * Nocturnal enuresis * Candidate for pharmacological treatment
Exclusion criteria
* Children who their parents did noted filled the informed consent form * Impossibility of follow up during the study period * History of seizure * History of rheumatologic disorders such as sjogren's disease
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| ّFrequency of nocturnal enuresis | 6 months | Number of participants with nocturnal enuresis |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Frequency of Epistaxis | 6 months | Number of participants with Epistaxis |
| Frequency of Rhinitis | 6 months | Number of participants with Rhinitis |
| Frequency of Chest pain | 6 months | Number of participants with Chest pain |
| Frequency of Abdominal pain | 6 months | Number of participants with Abdominal pain |
| Frequency of Vomiting | 6 months | Number of participants with Vomiting |
| Frequency of Ear ache | 6 months | Number of participants with Ear ache |
| Frequency of Headache | 6 months | Number of participants with Headache |
| Frequency of urinary incontinency | 6 months | Number of participants with urinary incontinency |
| Frequency of Seizure | 6 months | Number of participants with Seizure |
| Frequency of Xerostomia | 6 months | Number of participants with Xerostomia |
| Frequency of Xerophthalmia | 6 months | Number of participants with Xerophthalmia |
| Frequency of Blurred vision | 6 months | Number of participants with Blurred vision |
| Frequency of Dysphagia | 6 months | Number of participants with Dysphagia |
| Frequency of constipation | 6 months | Number of participants with constipation |
| Frequency of Diarrhea | 6 months | Number of participants with Diarrhea |
| Frequency of Increase in appetite | 6 months | Number of participants with Increase in appetite |
| Frequency of urgency | 6 months | Number of participants with urgency |
Countries
Iran
Outcome results
None listed