Limb Salvage
Conditions
Keywords
[E04.100.814.603]
Brief summary
This study aims to: 1. validate the Finnish version of the Musculoskeletal Tumor Society scale and the Toronto Extremity Salvage Score lower extremity sections and to 2. assess the functional ability and health-related quality of life (HRQoL) of lower extremity sarcoma patients who have undergone limb salvage surgery.
Detailed description
The first purpose of this study is to validate the Finnish version of the Musculoskeletal Tumor Society scale and the Toronto Extremity Salvage Score upper extremity sections. The second purpose is to chart the functional capabilities and health-related quality of life (HRQoL) of upper extremity sarcoma patients who have undergone limb salvage surgery with local or free flaps. Patient hospital records are retrospectively reviewed to chart the demographic and clinical data. The recruitment of patient takes place at the outpatient clinic of Department of Oncology, Helsinki University Hospital. The study includes a cross-sectional assessment at one year follow-up with five validated questionnaires. A follow-up is conducted three years after surgery in the outpatient clinic.
Interventions
PROCEDURELimb salvage
Sponsors
Helsinki University Central Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
10 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Lower extremity soft tissue sarcoma locating in between hip/gluteus to foot * No metastasis at the time of diagnosis * Undergone limb salvage surgery * A minimum of 1 year follow-up * Written consent * Age \> 18
Exclusion criteria
* Age \<18 * No limb-salvage surgery due to sarcoma
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Assessment of the functional ability after limb salvage | two to five years | Assessment of functional ability |
| Validity of the lower-limb Musculoskeletal Tumor Society score and the Toronto Extremity Salvage Score | two to five years | The validity is studied |
| Reliability of the lower-limb Musculoskeletal Tumor Society score and the Toronto Extremity Salvage Score | two to five years | The test-retest reliability is studied |
| Health-related quality of life after limb salvage | two to five years | Assessment of health-related quality of life |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Quality of Life Questionnaire-Core 30 | two to five years | Health-related quality of life assessment |
| The 15-dimensions health-related quality of life instrument | two to five years | Health-related quality of life assessment |
| The Musculoskeletal Tumor Society score lower extremity section | two to five years | Functional assessment of the reconstructed limb |
| The Toronto Extremity Salvage Score lower extremity section | two to five years | Functional assessment of the reconstructed limb |
Countries
Finland
Outcome results
None listed