Protein Ingestion and Muscle Carnitine Uptake

The Effects of an Insulinotropic Protein-carbohydrate Beverage on L- Carnitine Absorption and Muscle Carnitine Uptake

Status

Completed

Phases

Phase 1

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02535897

Enrollment

Registered

2015-08-31

Start date

2013-07-31

Completion date

2014-07-31

Last updated

2015-08-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Muscle, Skeletal

Brief summary

The purpose of this study is to assess the effects of a protein-carbohydrate beverage on the absorption of an orally ingested bolus of L-carnitine, compared to flavoured water and carbohydrate-only controls, and to determine whether increasing plasma carnitine availability can impact upon insulin-stimulated muscle carnitine uptake.

Interventions

DIETARY_SUPPLEMENTFlavoured water

DIETARY_SUPPLEMENTFlavoured water + carbohydrate

DIETARY_SUPPLEMENTFlavoured water + carbohydrate + protein

Study design

Allocation

RANDOMIZED

Intervention model

CROSSOVER

Primary purpose

BASIC_SCIENCE

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

MALE

Age

18 Years to 35 Years

Healthy volunteers

Yes

Inclusion criteria

* Healthy * Body mass index of 18-25 kg/cm2

Exclusion criteria

* Unhealthy * Smoker * Taking any medication that interferes with skeletal muscle metabolism

Design outcomes

Primary

Measure	Time frame	Description
Muscle carnitine uptake	180 minutes	Change in forearm carnitine uptake (measured using arterialised-venous - venous balance technique) in response to intervention.

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026