Study of the Interactions Between Dientamoba Fragilis and the Gut Microbiota

Status

Terminated

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02534272

Enrollment

Registered

2015-08-27

Start date

2016-02-16

Completion date

2019-03-29

Last updated

2025-03-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diarrhea

Brief summary

D.fragilis is an intestinal protozoon that feeds by phagocytosis of intestinal bacteria. The study aim to determine if the carriage of the intestinal parasite D.fragilis is associated to changes of gut microbiota in subjects presenting with or without intestinal symptoms.

Interventions

OTHERStool sampling and sequencing of gut microbiota.

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

for symptomatic group: * male/female aged at least of 18 years * subject with abdominal pain, diarrhea, bloating * no other known intestinal disease Inclusion Criteria for asymptomatic group: * male/female aged at least of 18 years * no known intestinal disease

Exclusion criteria

of symptomatic and asymptomatic groups: * chronic intestinal diseases such as IBD, IBS … * intake of antibiotic or probiotic within the 2 last months * subject in exclusion period * subject unable to understand information for a free consent to the study * subject in safeguarding justice or guardianship

Design outcomes

Primary

Measure	Time frame
16SrRNA copy numbers	Within the 2 days following inclusion

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026