Remote Ischemic Preconditioning in Liver Transplantation

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02534025

Acronym

RIRI

Enrollment

100

Registered

2015-08-27

Start date

2016-01-31

Completion date

2017-03-31

Last updated

2017-02-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Liver Transplanatation

Brief summary

Remote (upper arm) ischemic preconditioning in the donor of living donor liver transplanta to ameliorate the effect of reperfusion injury in recipients.

Detailed description

Upper arm ischemia will be induced by elevation of NIBP cuff pressure to 200 mm Hg for 5 minutes repeated four times 5 mniutes apart, aiming to decrease the effect of ischemia reperfusion in the graft liver.

Interventions

PROCEDUREIschemia preconditioining

Elavate blood pressure cuff pressure to 200

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

SINGLE (Subject)

Eligibility

Sex/Gender

ALL

Age

30 Years to 60 Years

Healthy volunteers

Inclusion criteria

* All candidates for living donor liver transplantation

Exclusion criteria

* Donors with peripheral vascular disease

Design outcomes

Primary

Measure	Time frame	Description
liver enzymes ( SGOT and SGPT) as indicator of graft injury	30 minutes	Hemodynamic effects of reperfusion ijury

Countries

Egypt

Contacts

Primary ContactAlRefaey Kandeel, MD

refa3ey2@yahoo.com+201008158591

Backup ContactAmr Yassen, MD

Amryassen@hotmail.com

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026