Web-based Genetic Research on Lupus

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02530944

Enrollment

5000

Registered

2015-08-21

Start date

2015-05-31

Completion date

2017-10-31

Last updated

2018-01-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Systemic Lupus Erythematosus

Keywords

Lupus, Systemic Lupus Erythematosus (SLE), genetic, online, genome wide association, systemic lupus erythematosus, genome wide association study (GWAS)

Brief summary

The goal of this new lupus research study is two-fold: first, to understand the genetic associations found between people's DNA and this disease, and second, to apply this understanding to drug development efforts with the investigator's partners at Pfizer.

Detailed description

Lupus is a difficult disease to diagnose and one that's difficult to manage, given the lack of specific medicines to treat lupus and the side-effects of current medications. The investigators believe genetics may play a critical role in developing better lupus diagnoses and treatments. If individuals are eligible to participate, the investigators will send a 23andMe DNA saliva kit at no cost. Participants will be asked to take a 15 minute online survey with questions about their lupus experience, symptoms and response to treatments, in addition to five additional bi-monthly short surveys and one final study survey during the 12-month participation. Learn more and join the lupus study today: https://www.23andme.com/lupus/

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

6 Years to No maximum

Healthy volunteers

Inclusion criteria

* diagnosed with lupus by a qualified physician. * consents to have 23andMe (via a partner) contact the physician to obtain medical record information * willing to submit a saliva sample for DNA testing and complete online surveys related to condition * at least 6 years old (minors under 18 require parental consent to enroll) * access to the internet * resides in the United States

Exclusion criteria

Design outcomes

Primary

Measure	Time frame	Description
Salivary DNA sample for genetic analysis	12 months	—
Online survey	12 months	Questions about lupus experience, symptoms and response to treatment

Countries

United States

Outcome results