Lipid Metabolism Disorders, Obesity
Conditions
Brief summary
In this trial, the investigators analyzed the effects of eight weeks of CLA supplementation associated with aerobic exercise on body fat and lipid profile in obese women.
Detailed description
The aim of this investigation was to analyze the effects of eight weeks of CLA supplementation associated with aerobic exercise on body fat and lipid profile in obese women. The investigators performed a randomized, double-blinded and placebo-controlled trial with 28 obese women who received 3.2 g/d of CLA or 4 g/d of olive oil (placebo group) while performing an 8-week protocol of aerobic exercise. Dietary intake (food record), body fat (DXA) and biochemical analysis (blood sample) were assessed before and after the intervention period.
Interventions
DIETARY_SUPPLEMENTCLA
CLA group received supplementation at a dose of 3.2 g/day (mixture of isomers of CLA isomers predominantly c9, t11 - 50% and c12, t10 - 80%). Aerobic exercise associated with CLA
BEHAVIORALPlacebo
Placebo group received 4 g/day of olive oil. Aerobic exercise
Sponsors
Universidade Estadual de Londrina
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 35 Years
Healthy volunteers
Yes
Inclusion criteria
* Had no signs or symptoms of disease * No orthopedic injuries * Must be inactive or moderately active (defined as performing any type of physical exercise less than twice a week) * Must be non-smokers * Must be free from the use of ergogenic aids * Had no metabolic disorders or chronic degenerative diseases * Not use drug therapy for body mass loss.
Exclusion criteria
* Had frequency to training sessions below 85% of the total sessions
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Body fat | 8 weeks | Dual-energy X-ray absorptiometry |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Total cholesterol | 8 weeks | Blood analysis |
| Triglycerides | 8 weeks | Blood analysis |
| High-density lipoprotein | 8 weeks | Blood analysis |
| Low-density lipoprotein | 8 weeks | Estimated by Friedewald formula |
| Arm fat | 8 weeks | Dual-energy X-ray absorptiometry |
| Leg fat | 8 weeks | Dual-energy X-ray absorptiometry |
| Trunk fat | 8 weeks | Dual-energy X-ray absorptiometry |
Other
| Measure | Time frame | Description |
|---|---|---|
| Body mass | 8 weeks | Urano, model PS 180 |
| Maximum oxygen uptake | 8 weeks | incremental treadmill test |
Countries
Brazil
Outcome results
None listed