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Progressive Strength in Hand Osteoarthritis

Effectiveness of a Progressive Resistance Strength Program on Hand Osteoarthritis: a Randomized Controlled Trial

Status
Completed
Phases
Phase 4
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02528630
Enrollment
60
Registered
2015-08-19
Start date
2013-10-31
Completion date
2015-10-31
Last updated
2017-02-23

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hand Osteoarthritis

Brief summary

Background: Hand osteoarthritis (OA) is highly prevalent, affecting 55-70% of the population over 55 years with an age-related progressive increase. The OA of interphalangeal (IF) and carpometacarpal joints may have varying degrees of deformity associated with pain, decreased of grip and pinch strength, decreased range of motion and functional impairment. Systematic reviews and meta-analyzes have shown the beneficial effect of exercise for lower limb OA, however for hand OA exercise is still used based on recommendations based on clinical experience and low quality studies, not allowing a conclusion about the effects of exercise in pain, function and strength in hand OA patients. Objective: assess the effectiveness of progressive resistance strength training program on pain, function and strength in hand OA patients. Methods: diagnostic of hand OA according to American College of Rheumatology of at least 1year, age over 50 years, both genders, pain in IF joints between 3-8 cm on a 10-cm numerical pain scale (NPS). Sixty patients who meet the eligibility criteria were randomized into exercise group (EG) and control group (CG). Both groups performed a session regarding joint protection and energy conservation before randomization. The EG performed a progressive resistance strength training program for intrinsic muscles of the hand for 12 weeks. The outcome measures were NPS; Australian/Canadian (AUSCAN) Hand Osteoarthritis Index and Cochin Hand Functional Scale for hand function; grip and pinch strengthening using the Hydraulic Hand Dynamometer and a pinch gauge dynamometer and satisfaction with the treatment using a Likert scale. A blinded evaluator performed the evaluations at baseline, 6 and 12 weeks after treatment baseline.

Interventions

OTHERProgressive resistance strength training program

Patients undergo to strength training for intrinsic muscles of the hand twice a week, during 12 weeks.

OTHERJoint protection and energy conservation advice

A session regarding joint protection and energy conservation for hands was done before randomization.

Sponsors

Federal University of São Paulo
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
50 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* diagnostic of hand OA according to american college of rheumatology of at least 1year; * age over 50 years; * both genders; * pain in interphalangeal joints between 3-8 cm on a 10-cm numerical pain scale

Exclusion criteria

* other joint disease in hands; * other rheumatic systemic disease; * surgery in hands or writs; * exercise or joint injection in hands in the previous 3 months; * disability to perform the exercises.

Design outcomes

Primary

MeasureTime frameDescription
Change in PainBaseline, after 6 and 12 weeksMeasured by a numerical pain scale

Secondary

MeasureTime frameDescription
Change in hand functionBaseline, after 6 and 12 weeksmeasured by AUSCAN
Change in Patient satisfaction with treatment6 and 12 weeksMeasured by a Likert scale
Change in grip strengthBaseline, after 6 and 12 weeksMeasured by a Grip Hydraulic Hand Dynamometer
Change in pinch stengthBaseline, after 6 and 12 weeksMeasured by pinch gauge dynamometer

Countries

Brazil

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026