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Modulation of Painful Perception

Modulation of Painful Perception

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02528578
Acronym
MODOU
Enrollment
74
Registered
2015-08-19
Start date
2013-06-30
Completion date
2015-11-30
Last updated
2017-09-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy

Keywords

healthy volunteers

Brief summary

The objective of the study is to evaluate in healthy volunteers, the influence of empathy on pain perception. It is widely accepted in the clinical management that the feeling of listening to the patients' pain would have a favorable influence on the pain, and conversely, the lack of listening would be aggravating. In this study, the volunteer will receive painful thermal stimuli in empathetic context (l, empathetic or non-empathetic) Two situations will oppose, one where the examiner neglect or minimize the suffering of the voluntary and the other or the contrary, the subject will receive empathy. The first part of the project is to verify that the pain is influenced by the empathetic context. The second part will be conducted functional MRI, which should isolate the brain regions affected by other people's empathy for pain.

Interventions

DEVICEthermal stimulation delivered by a thermode.

Empathetic context (neutral, empathetic, non-empathetic) when thermal stimulation

OTHERfunctional MRI

MRI realised with thermal stimulations and empathetic context (neutral, empathetic, non-empathetic) when thermal stimulation

Sponsors

Centre Hospitalier Universitaire de Saint Etienne
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 50 Years
Healthy volunteers
Yes

Inclusion criteria

* Right handed

Exclusion criteria

* Pregnant or lactating women, * Against-indications to MRI * Drug intake of less than 12 hours, * Neurological history or deficits, psychiatric, auditory or visual. * Decline to participate

Design outcomes

Primary

MeasureTime frame
Intensity of the perceived pain assessed by the volunteer by a analog scale (VAS) at each thermal stimulation.Day 0

Secondary

MeasureTime frame
blood-oxygen-level dependent (MRI)Day 0

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026