Determination of Perioperative Acute Kidney Injury Incidence

Perioperative Acute Kidney Injury Incidence and Risk Factors in Non-cardiac Surgery

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02521350

Enrollment

5000

Registered

2015-08-13

Start date

2015-06-30

Completion date

2016-06-30

Last updated

2015-08-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intensive Care Unit Syndrome

Keywords

Acute Kidney Injury, Surgery, Perioperative care

Brief summary

In the last few years, acute renal injury (AKI) definition has been significantly changed. In the light of the data obtained from multicenter international studies, acute renal injury was redefined according to RIFLE, AKIN and KDIGO criteria. The common criteria of all three criteria in acute renal failure is the increment of level of creatinine as 0.3 mg/dL or 50 % increment of respective basal value of serum creatinine. In the current study, older than 40 years patients with no specific gender, who will stay at least one night in hospital will be included and cardiovascular and urological surgery patients and patients with known renal insufficiency will be excluded. It was aimed to measure serum creatinine levels in all included patients at baseline and up to 24h after surgery and will be determined acute kidney injury incidence and risk factors according to new criteria.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

40 Years to 75 Years

Healthy volunteers

Inclusion criteria

* older than 40 years * no gender specified * patients who will stay at least one night in hospital * patient with normal renal function

Exclusion criteria

* patient with renal dysfunction and cardiovascular, urological surgery patients

Design outcomes

Primary

Measure	Time frame	Description
Change from baseline in serum creatinine levels at 24h after surgery	Serum creatinine levels will be measured at baseline and up to 24h after surgery	AKI incidence determination using 50 % or more than 0.3 mg/dL increment of creatinine levels
Correlation with use of drugs before surgery and serum creatinine level at 24h after surgery	Use of drug before surgery and serum creatinine level at 24h after surgery will be correlated.	—

Outcome results