A New Approach to a Personalized Patient Blood Management Program (pPBM) in Total Hip Arthroplasty (THA)

A New Approach to a Personalized Patient Blood Management Program in Total Hip Arthroplasty

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02519088

Enrollment

477

Registered

2015-08-10

Start date

2015-08-31

Completion date

2015-10-31

Last updated

2015-10-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative Anemia

Keywords

Homologous Blood Transfusion, Total Hip Replacement, Patient Blood Management

Brief summary

The study evaluates the patient related risk and predictive factors concerning perioperative homologous blood cell transfusion (erythrocyte concentrate ) in THA patients in one EndoCert max-certified orthopedic hospital in Germany. A patient oriented preoperative decision-making algorithm (a personalised Patient Blood Management or pPBM App) will be developed as a new patient-safety blood-sparing strategy. The aim is to increase the patient safety by using the pPBM App and to reach a more efficient management of resources.

Detailed description

Retrospective audit of 470 consecutive primary THA in 2013 and 2014

Interventions

None listed

Study design

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* primary THA on patients with coxarthrosis

Exclusion criteria

* any kind of old or acute fractures about the basin and hip * combined surgery, like first extracting a femur nail and than undergoing THA * any other kind of combined or simultaneous surgery * any kind of coagulopathy

Design outcomes

Primary

Measure	Time frame	Description
Events and circumstances of Homologous Blood Transfusion (erythrocyte concentrate transfusion)	participants will be followed for the duration of hospital stay, an expected average of 10 days	Multivariate analysis of predictive variables like age, sex, BMI, hip and belly circumference, chronic kidney disease, chronic cardio-vascular disease, chronic inflammatory disease, diabetes mellitus, cancer, ASA Score, cemented, hybrid or not cemented prosthesis, surgery duration, medication and hemoglobin level before surgery

Secondary

Measure	Time frame	Description
pPBM Computer Simulation	participants will be followed for the duration of hospital stay, an expected average of 10 days	Introducing the pPBM App as a safe blood-sparing strategy

Countries

Germany

Outcome results