Dynamics of Stroke Volume and Cardiac Output During Parabolic Flight, and Its Relationship to Intravascular Volume

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02518880

Acronym

DYMCO

Enrollment

Registered

2015-08-10

Start date

2010-03-31

Completion date

Unknown

Last updated

2015-08-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy Volunteers

Brief summary

To understand the cardiovascular reactions of the human body to changing conditions of gravity is an important aim of space science. In this context, cardiac output (CO) is a key value to estimate the human cardiovascular system. The main objective of this experiment is to determine the effects of parabolic flight on intravascular volume, and how these changes modulate the complex haemodynamics induced by the parabolas.

Interventions

OTHERParabolic flight

OTHERplasma volume measurements

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

BASIC_SCIENCE

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 55 Years

Healthy volunteers

Yes

Inclusion criteria

* healthy volunteers (men or women), * aged from 18 to 55, * affiliated to a Social Security system, * who accept to take part in the study, * who have given their written stated consent, * who already participated in parabolic flights (even in the same campaign) * All subjects will pass a medical examination similar to a standard aviation medical examination for private pilot aptitude. There will be no additional test performed for subject selection

Exclusion criteria

* person who took part in a previous biomedical research protocol, of which exclusion period is not terminated, * pregnant women

Design outcomes

Primary

Measure	Time frame
haemoglobin concentration	baseline

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026