Postoperative Pain
Conditions
Keywords
Tramadol, Postoperative analgesia, Infiltration, Cesarean section
Brief summary
This double-blind, randomized trial examined whether tramadol wound infiltration decreased postoperative pain following cesarean delivery under general anesthesia or reduced the need for analgesics in the immediate postoperative period. Patients in the tramadol group consumed significantly less morphine at all time intervals than those in the control group. The investigators suggest that the use of wound infiltration with tramadol may be a useful technique in patients who undergo cesarean section under general anesthesia to reduce postoperative pain, improve recovery, and facilitate early contact of mothers with their babies.
Interventions
DRUGTramadol
A preprepared 20 ml solution was subcutaneously infiltrated after closure of the uterine incision and the rectus fascia.
Sponsors
Yeditepe University Hospital
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
PREVENTION
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 35 Years
Healthy volunteers
Yes
Inclusion criteria
* Nulliparity * Gestation age between 37-40 weeks * CS under general anesthesia
Exclusion criteria
* Pre-eclampsia * Cardiovascular problems * Allergy to any of the study medications * Chronic preoperative pain * Regular analgesic use
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The primary outcome measure in this study was cumulative morphine consumption. | postoperative 24 hours | The measure of need for analgesics in the immediate postoperative period in this study was cumulative morphine consumption. |
Countries
Turkey (Türkiye)
Outcome results
None listed