Improvement in Acoustic Voice Characteristics in Functional Dysphonia After Therapy

Which Instrumental Acoustic Voice Parameters Indicate Vocal Improvement After Voice Therapy in Patients With Functional Dysphonia

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02518425

Enrollment

Registered

2015-08-07

Start date

2015-04-30

Completion date

2015-12-31

Last updated

2016-05-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Functional Voice Disorder

Brief summary

In a retrospective analysis of already existing clinical assessment data from patients with functional voice disorders the following aspects will be sampled, encoded and analysed: Outcomes pre and post treatment of 1. subjective voice symptoms measured by Voice Handicap Index (VHI-9i), 2. perceptual voice symptoms according to Grading-Roughness-Breathiness-Asthenia-Strain Scale (GRBAS Scale), 3. instrumental acoustic analysis parameters Jitter (%), speaking voice profile: mean and range of speaking pitch and intensity, max. intensity and mean pitch of calling voice, singing voice: min./max. and range of pitch and intensity, maximum phonation time, Dysphonia Severity Index (DSI).

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

20 Years to 70 Years

Healthy volunteers

Inclusion criteria

* informed consent; patients 20 to 70 years with functional voice disorder; -diagnostics and voice therapy at University Hospital Zurich; * full pre- and post treatment voice assessment (videostroboscopy, subjective self- assessment, instrumental acoustic and perceptual analysis).

Exclusion criteria

* known neurologic and psychiatric disease, * hearing disorder, * surgery of the head and neck area or intubation (for any reason) in last 18 months.

Design outcomes

Primary

Measure	Time frame	Description
Instrumental acoustic voice parameters	Before (initial diagnosis) and after voice therapy, expected average of 11-20 weeks after initial diagnosis)	Instrumental acoustic parameters are determined by a computer-assisted analysis of voice recordings. In the present study the following parameters are measured before and after voice therapy: Jitter % (deviation of fundamental frequency), mean and range of speaking pitch and intensity, maximum intensity and mean pitch of calling voice, minimum and max. and range of pitch and intensity of the singing voice, and the composite measure Dysphonia Severity Index (DSI).

Secondary

Measure	Time frame	Description
Subjective voice symptoms	Before (initial diagnosis) and after voice therapy, expected average of 11-20 weeks after initial diagnosis)	Subjective voice symptoms are measured before and after voice therapy by the patient questionnaire Voice Handicap Index (VHI-9i).
Perceptual voice symptoms	Before (initial diagnosis) and after voice therapy, expected average of 11-20 weeks after initial diagnosis)	Perceptual (hearable) voice symptoms are determined by the examiner before and after voice therapy using GRBAS Scale (Grading-Roughness-Breathiness-Asthenia-Strain Scale).

Countries

Switzerland

Outcome results