Suicide Attempts
Conditions
Keywords
emergency department, epidemiology, prehospital care, dispatch, acute self poisoning
Brief summary
Acute self poisoning is a leading cause of suicide attempts and leads to frequent emergency department visits. However, the exact epidemiology of acute self poisoning is not known. The description of the clinical pathway and the characteristics of patients with acute self poisoning could lead to an improvement in emergency care. The Investigators will conduct a 48h observational study in emergency services in France. Investigators primary objective is to gathered epidemiological clinical and treatment data during emergency dispatch, prehospital care and inhospital emergency care.
Detailed description
Acute self poisoned patients will be prospectively and anonymously recruited by emergency physicians in charge during two days. Acute self poisoning is define as follow: intentional medicine intake in the 24h hours before emergency department admission. Epidemiological, clinical, toxicological and treatment data will be gathered. Outcome of patient will be prospectively assessed at 30days. All data will be transmitted to the principal investigators. Then, 20% of the data will be monitored by an independent committee. Exhaustivity will be retrospectively assessed by the number of inclusions in 10 emergency centers divided by the total number of possible inclusions in these centers. Finally, an independent statistician will be in charge of the analysis.
Interventions
OTHERNo intervention
No intervention is planned
Sponsors
French Society of Emergency Medicine
University Hospital, Grenoble
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* acute self poisoning defined as the intentional intake (oral, nasal, injection etc.) of medicines during the 24h before first medical contact
Exclusion criteria
* cardiac arrest at first medical contact (dispatch or physician) * acute self poisoning without any medication intake * non intentional poisoning
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Percentage of each drug class | 48h |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Mortality according to drug class ingestion | 30 days | — |
| ICU admission according to drug class ingestion | 30 days | — |
| icu admission (percentage) | 48h | — |
| percentage of errors according to the Grenoble clinical decision rule | 30 days | — |
| multivariate analysis to describe factors associated with ICU admission | 30 days | — |
| multivariate analysis to describe factors associated with mobile intensive care unit dispatch | 30 days | — |
| odds ratio of drug classes according to sexe and age | 48h | — |
| Time (median) of admission according unit of admission | 48h | — |
| prehospital and inhospital mortality | 30 days | — |
| percentage of each antidotal treatment | 48h | — |
| mobile intensive care unit (percentage) dispatch | 30 days | — |
| Age according to drug classes ingestion | 48h | Median age compared according drug classes ingestion |
| Gender according to drug classes ingestion | 48h | Pourcentage of gender compared according drug classes ingestion |
| Time (median) of admission according to drug classes ingestion | 48h | — |
| number of participants with poisoning incident | 48h | — |
Outcome results
None listed