Borderline Personality Disorder, Stress Disorders, Post-Traumatic
Conditions
Keywords
Borderline Personality Disorder, comorbid Posttraumatic Stress Disorder, Narrative Exposure Therapy, Dialectical-Behavioral Therapy
Brief summary
Narrative Exposure Therapy (NET) is an evidence-based trauma-focussed treatment, suitable for survivors of prolonged and repeated exposure to traumatic stress and childhood adversity. Patients with Borderline Personality Disorder (BPD) often suffer from a comorbid Posttraumatic Stress Disorder (PTSD) caused by multiple traumatic events. Therapeutic aims are the reduction of PTSD-Symptoms in these patients via activation of associative neural networks related to traumatic experiences and habituation of fear and the placement of traumatic experiences in a reconstructed, detailed and consistent autobiography. This practice enables the processing of and coping with painful memories and the construction of clear contingencies of dangerous and safe conditions, generally leading to significant emotional recovery. The investigators assume that using NET the reduction of PTSD symptom severity is greater compared to treatment by Dialectical-Behavioral Therapy (DBT).
Interventions
BEHAVIORALNarrative Exposure Therapy
Narrative Exposure Therapy (NET) is based on Testimony Therapy in combination with cognitive behavioural exposure techniques and elements of client-centered counselling. The clients can restore their autobiographic memories about their traumatic experiences. In this way fragmentary memories are transformed into a coherent narrative structure. This practice enables the processing of painful emotions and the construction of clear contingencies of dangerous and safe conditions, generally leading to significant emotional recovery. Therapeutic aims are the reduction of PTSD-Symptomload via activation of fear-network and habituation of fear and the placement of traumatic experiences in a reconstructed, detailed and consistent autobiography. NET will be applied in eight sessions (90-120min/session) in a standardized, manualized manner.
BEHAVIORALDialectical Behavior Therapy
Dialectical behavior therapy is a cognitive behavioral treatment program developed by Marsha Linehan to treat suicidal clients meeting criteria for BPD. It directly targets suicidal behavior, behaviors that interfere with treatment delivery, and other dangerous, severe, or destabilizing behaviors. Via standard DBT patients improve behavioral capabilities, motivation for skillful behavior, generalization of gains to the natural environment, structuring the treatment environment so that it reinforces functional rather than dysfunctional behaviors. It also targets the therapist capabilities and motivation to treat patients effectively. Patients get weekly individual psychotherapy (1 h/wk), group skills training (3.75 h/wk), a weekly therapist consultation team meetings.
BEHAVIORALStandard Inpatient Care
Unspecific group therapy that is identical in both groups (music therapy etc.)
OTHERWaiting List
Treatment as usual in the community (no DBT, no exposure of trauma memories)
Sponsors
Evangelisches Krankenhaus Bielefeld gGmbH
Study design
Allocation
RANDOMIZED
Intervention model
FACTORIAL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* age ≥ 18 years * DSM-IV-TR diagnoses of BPD and PTSD * legal competence * none or stable medication * illegal drug abstinence for at least the last 6 months * capacity to consent and contract
Exclusion criteria
* other severe mental disorders (e.g., bipolar disorder, acute psychosis) * simultaneous consumption of drugs * simultaneous participation in other treatment-studies * pregnancy or breastfeeding * lack of capability to negotiate a no-suicide agreement * suicide attempt or attempts during the 8 weeks prior to start of treatment * perpetrator-contact * Body Mass Index (BMI) \< 16
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change from first investigation in Posttraumatic Symptom Severity at 18 months (Clinician-Administered PTSD Scale; CAPS) | first investigation (t1), after waiting list (3 months, t2), directly after therapy (3 months, t1), 1 year after therapy (15 months, t3) |
Secondary
| Measure | Time frame |
|---|---|
| Change from first investigation in Borderline Symptome Severity at 18 months(Borderline Symptom Liste; BSL) | first investigation (t1), after waiting list (3 months, t2), directly after therapy (6 months, t3), 1 year after therapy (18 months, t4) |
| Change from first investigation in Severity of Dissociative Symptoms at 18 months (Fragebogen zu Dissoziativen Symptome ;FDS) | first investigation (t1), after waiting list (3 months, t2), directly after therapy (6 months, t3), 1 year after therapy (18 months, t4) |
| Change from first investigation in Severity of Depressive Symptoms at 18 months (Becks Depressions Inventar II, BDI-II) | first investigation (t1), after waiting list (3 months, t2), directly after therapy (6 months, t3), 1 year after therapy (18 months, t4) |
| Change from first investigation in Quality of Life at 12 months (WHO-Qualitiy of Life; WHOQOL) | first investigation (t1), after waiting list (3 months, t2), directly after therapy (6 months, t3), 1 year after therapy (18 months, t4) |
Countries
Germany
Outcome results
None listed