The Effect of Altered Gravity Condition on Postural Control

Status

UNKNOWN

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT02517229

Acronym

POSTURGRAV

Enrollment

Registered

2015-08-06

Start date

2012-09-30

Completion date

Unknown

Last updated

2015-08-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy

Keywords

volunteers

Brief summary

The scientific goal of this experiment is to evaluate changes in balance control in response to microgravity during reactive balance tasks. For that purpose, kinematic and neuromuscular parameters under microgravity are compared to normal gravity conditions. To induce postural responses among the test subjects, an electromagnetic maneuverable postural platform will be used in order to randomly elicit perturbations. Postural reactions will be quantified by means of mechanical and electromyographic data. In Addition, peripheral nerve stimulation will be used to assess the spinal excitability by means of H-reflex recordings. H-reflex measurements were chosen as they allow reliable information about inhibitory and facilitatory mechanisms taking place at the spinal level.

Interventions

OTHERParabolic flight

OTHERbalance control measurements

DEVICEelectromagnetic maneuverable postural platform

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

BASIC_SCIENCE

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

21 Years to 65 Years

Healthy volunteers

Yes

Inclusion criteria

* Healthy volunteers (men or women) * Aged from 21 to 65 * Affiliated to a Social Security system and, for non-French resident, holding a European Health Insurance Card (EHIC) * Who accepted to take part in the study * Who have given their written stated consent * Who has passed a medical examination similar to a standard aviation medical examination for private pilot aptitude. There will be no additional test performed for subject selection.

Exclusion criteria

* Person who took part in a previous biomedical research protocol, of which exclusion period is not terminated * Person with medical history of neurological disorders * Person with medical history of musculoskeletal disorders of the lower limbs, especially of the ankle and knee joint. * Pregnant women

Design outcomes

Primary

Measure	Time frame
balance skill, expressed by the postural sway in mm	baseline
neuromuscular activity, expressed by the Electromyograpy (EMG)-amplitudes	baseline
spinal excitability, expressed by H-Reflexes	baseline

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026