Practice of Mechanical Ventilation in Patients With Severe Brain Injury in China

A Survey on the Practice of Mechanical Ventilation Among Patients With Severe Brain Injury in China: a Prospective Observational Study

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT02517073

Enrollment

104

Registered

2015-08-06

Start date

2015-08-31

Completion date

2015-09-30

Last updated

2016-01-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Respiration, Artificial

Keywords

mechanical ventilation, epidemiology, intensive care unit, national survey

Brief summary

The mechanical ventilation strategy has changed over years worldwide. Several international researches have been conducted to study the association of the use of mechanical ventilation with clinical outcomes. In this prospective, multicenter, cross-sectional survey, the practice of mechanical ventilation among patients with severe brain injury will be investigated in 70 intensive care units in China.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

1. older than 18 years 2. with severe brain injury (including severe traumatic brain injury, ischemic stroke, subarachnoid hemorrhage, spontaneous intracerebral hemorrhage, hypoxic-ischemic encephalopathy, intracranial tumor, intracranial infection and idiopathic epilepsy) 3. mechanical ventilated for at least 24 hours before the time of on-spot survey

Exclusion criteria

1. undergoing a spontaneous breathing trial (SBT) at the time of on-spot survey 2. underwent at least once SBT in the preceding 24 hours before time of on-spot survey 3. enrolled in another trial

Design outcomes

Primary

Measure	Time frame	Description
Number of patients receiving control and assist mode of mechanical ventilation	During 1 hour of on-spot survey	Control mode is defined as volume or pressure control ventilation. Assist mode is defined as synchronized intermittent mandatory ventilation and pressure support ventilation.

Secondary

Measure	Time frame
The settings of tidal volume, inspiratory pressure, and positive end-expiratory pressure in enrolled patients	During 1 hour of on-spot survey
Duration of mechanical ventilation	60 days after on-spot survey
Number of patients liberated from mechanical ventilation	60 days after on-spot survey
Neurological outcome by Glasgow Outcome Scale	60 days after on-spot survey

Countries

China

Outcome results