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Effects of PEEP on Optic Nerve Sheath Diameter During Robot-Assisted Laparoscopic Prostatectomy

Effects of Positive End-Expiratory Pressure Ventilation on Optic Nerve Sheath Diameter in Patients Undergoing Robot-Assisted Laparoscopic Prostatectomy

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT02516566
Enrollment
38
Registered
2015-08-06
Start date
2015-09-30
Completion date
2015-11-30
Last updated
2015-12-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Other Surgical Procedures

Keywords

Positive end-expiratory pressure ventilation, Optic nerve sheath diameter

Brief summary

The investigators aim to investigate the effects of positive end-expiratory pressure ventilation on intracranial pressure assessed by sonographic optic nerve sheath diameter in patients undergoing robot-assisted laparoscopic prostatectomy.

Detailed description

Effects of positive end-expiratory pressure ventilation on intracranial pressure have not been evaluated in patients undergoing laparoscopic surgery. We aim to investigate the effects of positive end-expiratory pressure ventilation on intracranial pressure assessed by sonographic optic nerve sheath diameter in patients undergoing robot-assisted laparoscopic prostatectomy.

Interventions

OTHERPEEP

Mechanical ventilation with PEEP 8 cmH2O

Sponsors

Asan Medical Center
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)

Eligibility

Sex/Gender
MALE
Age
20 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Patients who are scheduled to undergo robot-assisted laparoscopic prostatectomy

Exclusion criteria

* Patients who have cerebrovascular disease or history of cerebrovascular disease * Patients who are younger than 20 years

Design outcomes

Primary

MeasureTime frame
Optic nerve sheath diameterintraoperative

Secondary

MeasureTime frame
Peak airway pressureintraoperative
Arterial blood pressureintraoperative
Heart rateintraoperative
Arterial carbon dioxide tensionintraoperative

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 27, 2026