Pneumonia
Conditions
Keywords
pneumonia, Exacerbation, physiotherapy, hospitalization
Brief summary
Acute respiratory infections are the fourth cause of hospitalization in elderly. Various studies have examined the impact of hospitalization in patients with respiratory pathology, showing the need of interventions in order to reduce the impact of hospitalization. The objective of this study is to examine whether a physical therapy intervention can reduce impairment in patients hospitalized due to pneumonia.
Detailed description
Acute respiratory infections are the fourth cause of hospitalization in elderly. Hospital admissions due to pneumonia range from the 1.1 and 4 per 1,000 patients, increasing with age. Hospitalization causes a decline in physical and functional status. Physical impairment involves a higher risk of disability and mortality in elderly people. Various studies have examined the impact of hospitalization in patients with respiratory pathology, and it has been shown that hospitalization implies a significant physical impairment in patients admitted for pneumonia showing that this deterioration increases with age. That highlights the need of interventions in order to reduce the impact of hospitalization. The objective of this study is to examine whether a physical therapy intervention can reduce impairment in patients hospitalized due to pneumonia.
Interventions
DRUGcephalosporin with or without erythromycin
Second- or third-generation cephalosporin (cefuroxime, cefotaxime, or ceftriaxone) with or without erythromycin, given parenterally; parenteral therapy should continue until the patient has been afebrile for more than 24 hours and oxygen saturation exceeds 95 percent.
The physiotherapy treatment will be performed during the hospitalization, every day during 45-60 minutes added to the standard medical treatment. I will include breathing exercises, electrostimulation in quadriceps with voluntary contraction and exercises with theraband.
Sponsors
Universidad de Granada
Study design
Allocation
RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
SINGLE (Investigator)
Eligibility
Sex/Gender
ALL
Age
65 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Diagnosis of pneumonia. * No contraindication of physiotherapy. * Signed written consent. * Medical approval for inclusion.
Exclusion criteria
* Contraindications of physiotherapy. * Neurological, orthopedic or heart disease. * Prosthetic devices in lower limbs.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Exercise capacity | Participants will be followed for the duration of hospital stay, an expected average of 8 days | Five times sit to stand test (5STS) will be used to assess exercise capacity, 5STS is a simple assessment tool that is feasible in all healthcare settings, and may be a rapid method of assessing changes in exercise capacity in COPD and screening for poor physical functioning individuals. |
| Muscle strength | Participants will be followed for the duration of hospital stay, an expected average of 8 days | Quadriceps strength will be assessed with a portable dynamometer. The test will be performed as previously reported. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Dyspnea perception | Participants will be followed for the duration of hospital stay, an expected average of 8 days | Dyspnea perception will be assessed with Borg modified scale. Patients will classify their breathlessness between 0 and 10. |
| Quality of life | Participants will be followed for the duration of hospital stay, an expected average of 8 days. | EuroQol-5D (EQ-5D) will be used to assess quality of life. EQ-5D is a generic questionnaire and consists of two parts, the EQ-5D Visual analogue scale (VAS) and the EQ-5D index. The EQ-5D VAS consists on a vertical rating scale from 0 to 100 (0 = death/worst possible health state and 100 = best possible health state). The EQ-5D index is a five-item questionnaire (mobility, self-care, usual activity, pain/discomfort and anxiety/depression). Each item has three levels: no problem, some problem and severe problem. |
| Respiratory function | Participants will be followed for the duration of hospital stay, an expected average of 8 days | Spirometry is regarded as the gold standard measure of respiratory function. Spirometry will be performed according to the American Thoracic Society (ATS) criteria. |
| Functionality | Participants will be followed for the duration of hospital stay, an expected average of 8 days. | The London Chest Activity of Daily Living (LCADL) is a valid tool that is validated to measure breathlessness during daily activities. It is a 15-item questionnaire divided in 4 domains: self-care (4 items), domestic (6 items) physical activity (2 items) and leisure (3 items). |
| Fatigue | Participants will be followed for the duration of hospital stay, an expected average of 8 days. | Fatigue will be assessed with the Fatigue Severity Scale (FSS). The FSS is a nine-item instrument designed to assess fatigue as a symptom of a variety of different chronic conditions and disorders. The scale addresses fatigue's effects on daily functioning, querying its relationship to motivation, physical activity, work, family, and social life, and asking respondents to rate the ease with which they are fatigued and the degree to which the symptom poses a problem for them. |
| Mood | Participants will be followed for the duration of hospital stay, an expected average of 8 days. | Mood in these patients will be measured by the Hospital Anxiety and Depression Scale. |
Other
| Measure | Time frame | Description |
|---|---|---|
| Dependency levels | Baseline | Dependency levels will be evaluated with the Functional Independence Measure (FIM). It is an 18-item, 7-level scale developed to uniformly assess severity of patient disability and medical rehabilitation functional outcome. |
| Comorbidities | Baseline | Charlson Comorbidity Index will be used to assess the comorbidities of the patients, it is a simple and valid method of estimating risk of death from comorbid disease. It contains 19 categories of comorbidity and predicts the ten-year mortality for a patient who may have a range of co-morbid conditions. Each condition is assigned with a score of 1, 2, 3 or 6 depending on the risk of dying associated with this condition. |
| Nutritional status | Baseline | Nutritional status was evaluated with Mini nutritional assessment (MNA) test, that is validated to provide a single, rapid assessment of nutritional status in elderly patients in outpatient clinics, hospitals, and nursing homes. The MNA test is composed of simple measurements and brief questions that can be completed in about 10 min. |
Countries
Spain
Contacts
Primary ContactMarie Carmen Valenza, PhD
Backup ContactMarie Carmen Valenza, PhD
Outcome results
None listed